Centro de Investigación en Medicina Molecular e Enfermidades Crónicas (CIMUS)
Centro singular


Instituto de Investigaciones Biomédicas Alberto Sols
Madrid, EspañaPublicacións en colaboración con investigadores/as de Instituto de Investigaciones Biomédicas Alberto Sols (29)
2024
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Plasma membrane remodeling determines adipocyte expansion and mechanical adaptability
Nature Communications , Vol. 15, Núm. 1
2023
2022
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Effects of a Mealworm (Tenebrio molitor) Extract on Metabolic Syndrome-Related Pathologies: In Vitro Insulin Sensitivity, Inflammatory Response, Hypolipidemic Activity and Oxidative Stress
Insects, Vol. 13, Núm. 10
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Modulation of hypothalamic AMPK phosphorylation by olanzapine controls energy balance and body weight
Metabolism: Clinical and Experimental, Vol. 137
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Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue
Redox Biology, Vol. 54
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Temperature modulates systemic and central actions of thyroid hormones on BAT thermogenesis
Frontiers in Physiology, Vol. 13
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p38 MAPK priming boosts VSMC proliferation and arteriogenesis by promoting PGC1α-dependent mitochondrial dynamics
Scientific Reports, Vol. 12, Núm. 1
2021
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Increased hypothalamic anti‐inflammatory mediators in non‐diabetic insulin receptor substrate 2‐deficient mice
Cells, Vol. 10, Núm. 8
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RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness
Developmental Cell, Vol. 56, Núm. 12, pp. 1727-1741.e7
2020
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Adipose tissue as a target for second-generation (atypical) antipsychotics: A molecular view
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, Vol. 1865, Núm. 2
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Aripiprazole cytotoxicity coincides with activation of the unfolded protein response in human hepatic cells
Journal of Pharmacology and Experimental Therapeutics, Vol. 374, Núm. 3, pp. 452-461
2019
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New flavonoid–N,N-dibenzyl(N-methyl)amine hybrids: Multi-target-directed agents for Alzheimer´s disease endowed with neurogenic properties
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 34, Núm. 1, pp. 712-727
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Second-generation antipsychotics and dysregulation of glucose metabolism: Beyond weight gain
Cells, Vol. 8, Núm. 11
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TGFβ2-induced senescence during early inner ear development
Scientific Reports, Vol. 9, Núm. 1
2018
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Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 156, pp. 534-553
2017
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Pharmacological tools based on imidazole scaffold proved the utility of PDE10A inhibitors for Parkinson's disease
Future Medicinal Chemistry, Vol. 9, Núm. 8, pp. 731-748
2016
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New cinnamic - N-benzylpiperidine and cinnamic - N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties
European Journal of Medicinal Chemistry, Vol. 121, pp. 376-386
2015
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Thyroid cancer GWAS identifies 10q26.12 and 6q14.1 as novel susceptibility loci and reveals genetic heterogeneity among populations
International Journal of Cancer, Vol. 137, Núm. 8, pp. 1870-1878
2014
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Modulation of cAMP-specific PDE without emetogenic activity: New sulfide-like PDE7 inhibitors
Journal of Medicinal Chemistry, Vol. 57, Núm. 20, pp. 8590-8607
2013
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XProgrammed cell senescence during mammalian embryonic development
Cell, Vol. 155, Núm. 5, pp. 1104