Publikationen in Zusammenarbeit mit Forschern von Instituto de Investigaciones Biomédicas Alberto Sols (22)

2022

  1. Mitochondrial bioenergetics boost macrophage activation, promoting liver regeneration in metabolically compromised animals

    Hepatology, Vol. 75, Núm. 3, pp. 550-566

  2. Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue

    Redox Biology, Vol. 54

  3. Temperature modulates systemic and central actions of thyroid hormones on BAT thermogenesis

    Frontiers in Physiology, Vol. 13

  4. p38 MAPK priming boosts VSMC proliferation and arteriogenesis by promoting PGC1α-dependent mitochondrial dynamics

    Scientific Reports, Vol. 12, Núm. 1

2021

  1. RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness

    Developmental Cell, Vol. 56, Núm. 12, pp. 1727-1741.e7

2019

  1. New flavonoid–N,N-dibenzyl(N-methyl)amine hybrids: Multi-target-directed agents for Alzheimer´s disease endowed with neurogenic properties

    Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 34, Núm. 1, pp. 712-727

  2. TGFβ2-induced senescence during early inner ear development

    Scientific Reports, Vol. 9, Núm. 1

2018

  1. Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease

    European Journal of Medicinal Chemistry, Vol. 156, pp. 534-553

2017

  1. Pharmacological tools based on imidazole scaffold proved the utility of PDE10A inhibitors for Parkinson's disease

    Future Medicinal Chemistry, Vol. 9, Núm. 8, pp. 731-748

2016

  1. New cinnamic - N-benzylpiperidine and cinnamic - N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties

    European Journal of Medicinal Chemistry, Vol. 121, pp. 376-386

2015

  1. Thyroid cancer GWAS identifies 10q26.12 and 6q14.1 as novel susceptibility loci and reveals genetic heterogeneity among populations

    International Journal of Cancer, Vol. 137, Núm. 8, pp. 1870-1878

2014

  1. Modulation of cAMP-specific PDE without emetogenic activity: New sulfide-like PDE7 inhibitors

    Journal of Medicinal Chemistry, Vol. 57, Núm. 20, pp. 8590-8607

2013

  1. XProgrammed cell senescence during mammalian embryonic development

    Cell, Vol. 155, Núm. 5, pp. 1104

2012

  1. Direct promoter induction of p19Arf by Pit-1 explains the dependence receptor RET/Pit-1/p53-induced apoptosis in the pituitary somatotroph cells

    Oncogene, Vol. 31, Núm. 23, pp. 2824-2835

  2. Effect of phosphodiesterase 7 (PDE7) inhibitors in experimental autoimmune encephalomyelitis mice. Discovery of a new chemically diverse family of compounds

    Journal of Medicinal Chemistry, Vol. 55, Núm. 7, pp. 3274-3284

  3. Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model

    European Journal of Medicinal Chemistry, Vol. 47, Núm. 1, pp. 175-185

  4. Synthesis and biological evaluation of 1α,25-dihydroxyvitamin D 3 analogues with a long side chain at C12 and short C17 side chains

    Journal of Medicinal Chemistry, Vol. 55, Núm. 20, pp. 8642-8656

2010

  1. Hyaluronic acid/chitosan-g-poly(ethylene glycol) nanoparticles for gene therapy: An application for p DNA and siRNA delivery

    Pharmaceutical Research, Vol. 27, Núm. 12, pp. 2544-2555

  2. Regional decrease of subcutaneous adipose tissue in patients with type 2 familial partial lipodystrophy is associated with changes in thyroid hormone metabolism

    Thyroid, Vol. 20, Núm. 4, pp. 419-424

2005

  1. Generation of DNA double-strand breaks by two independent enzymatic activities in nuclear extracts

    Journal of Molecular Biology, Vol. 351, Núm. 5, pp. 995-1006