Publicacións en colaboración con investigadores/as de Universidade Do Porto (109)

2023

  1. 2H-chromene and 7H-furo-chromene derivatives selectively inhibit tumour associated human carbonic anhydrase IX and XII isoforms

    Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 38, Núm. 1

  2. 8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies

    European Journal of Medicinal Chemistry, Vol. 248

  3. Cytogenotoxicity assessment of 3-(3,4-dihydroxyphenyl)-7,8-dihydroxycoumarin on HepG2/C3A cells and leukocytes

    Journal of Applied Toxicology, Vol. 43, Núm. 2, pp. 323-334

  4. In silico approaches to develop new phenyl-pyrimidines as glycogen synthase kinase 3 (GSK-3) inhibitors with halogen-bonding capabilities: 3D-QSAR CoMFA/CoMSIA, molecular docking and molecular dynamics studies

    Journal of Biomolecular Structure and Dynamics, Vol. 41, Núm. 22, pp. 13250-13259

  5. Modulating Cytotoxicity with Lego-like Chemistry: Upgrading Mitochondriotropic Antioxidants with Prototypical Cationic Carrier Bricks

    Journal of Medicinal Chemistry, Vol. 66, Núm. 3, pp. 1835-1851

  6. Oxidation-labile linkers for controlled drug delivery

    Bioorganic and Medicinal Chemistry Letters, Vol. 87

  7. Phytochemical Analysis and Antiproliferative Activity of Ulex gallii Planch. (Fabaceae), a Medicinal Plant from Galicia (Spain)

    Molecules, Vol. 28, Núm. 1

  8. Propargylamine: an important moiety in drug discovery

    Future Medicinal Chemistry, Vol. 15, Núm. 1, pp. 211-224

2022

  1. A comprehensive ethnobotanical profile of Ocimum campechianum (Lamiaceae): from traditional medicine to phytochemical and pharmacological evidences

    Plant Biosystems, Vol. 156, Núm. 6, pp. 1388-1404

  2. Coumarin-Resveratrol-Inspired Hybrids as Monoamine Oxidase B Inhibitors: 3-Phenylcoumarin versus trans-6-Styrylcoumarin

    Molecules, Vol. 27, Núm. 3

  3. Design and synthesis of chromone-based monoamine oxidase B inhibitors with improved drug-like properties

    European Journal of Medicinal Chemistry, Vol. 239

  4. Synthesis and Vasorelaxant Activity of Nitrate−Coumarin Derivatives

    ChemMedChem, Vol. 17, Núm. 21

  5. Synthesis and study of the trypanocidal activity of catechol-containing 3-arylcoumarins, inclusion in β-cyclodextrin complexes and combination with benznidazole

    Arabian Journal of Chemistry, Vol. 15, Núm. 3

  6. Thiocoumarins: From the Synthesis to the Biological Applications

    Molecules, Vol. 27, Núm. 15

  7. Treating neurodegenerative diseases with multitarget drugs: an interview with Maria João Matos

    Future Medicinal Chemistry, Vol. 14, Núm. 12, pp. 847-850

2021

  1. 3-phenylcoumarins as a privileged scaffold in medicinal chemistry: The landmarks of the past decade

    Molecules, Vol. 26, Núm. 21

  2. 4-Oxoquinolines and monoamine oxidase: When tautomerism matters

    European Journal of Medicinal Chemistry, Vol. 213

  3. 7-Amidocoumarins as Multitarget Agents against Neurodegenerative Diseases: Substitution Pattern Modulation

    ChemMedChem, Vol. 16, Núm. 1, pp. 179-186

  4. Chemical and biological analysis of 4-acyloxy-3-nitrocoumarins as trypanocidal agents

    Arabian Journal of Chemistry, Vol. 14, Núm. 3

  5. Combined 3D-QSAR and docking analysis for the design and synthesis of chalcones as potent and selective monoamine oxidase B inhibitors

    Bioorganic Chemistry, Vol. 108