I+D de fármacos
GI-1606
EDDY
SOTELO PEREZ
Catedrático de universidade
Publicacións nas que colabora con EDDY SOTELO PEREZ (42)
2021
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3,4-Dihydropyrimidin-2(1H)-ones as Antagonists of the Human A2B Adenosine Receptor: Optimization, Structure-Activity Relationship Studies, and Enantiospecific Recognition
Journal of medicinal chemistry, Vol. 64, Núm. 1, pp. 458-480
2018
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Three-Dimensional Printing in Catalysis: Combining 3D Heterogeneous Copper and Palladium Catalysts for Multicatalytic Multicomponent Reactions
ACS Catalysis, Vol. 8, Núm. 1, pp. 392-404
2017
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3-Oxopyridazin-5-yl-Chalcone Hybrids: Potent Antiplatelet Agents That Prevent Glycoprotein IIb/IIIa Activation
ChemistrySelect, Vol. 2, Núm. 17, pp. 4920-4933
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An efficient and recyclable 3D printed α-Al2O3 catalyst for the multicomponent assembly of bioactive heterocycles
Applied Catalysis A: General, Vol. 530, pp. 203-210
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Enantiospecific Recognition at the A2B Adenosine Receptor by Alkyl 2-Cyanoimino-4-substituted-6-methyl-1,2,3,4-tetrahydropyrimidine-5-carboxylates
Journal of Medicinal Chemistry, Vol. 60, Núm. 8, pp. 3372-3382
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Multicomponent Assembly of the Kinesin Spindle Protein Inhibitor CPUYJ039 and Analogues as Antimitotic Agents
ACS Combinatorial Science, Vol. 19, Núm. 3, pp. 153-160
2016
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3D printing of a heterogeneous copper-based catalyst
Journal of Catalysis, Vol. 334, pp. 110-115
2015
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Integrated Ugi-Based Assembly of Functionally, Skeletally, and Stereochemically Diverse 1,4-Benzodiazepin-2-ones
Journal of Organic Chemistry, Vol. 80, Núm. 3, pp. 1533-1549
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Pyrazin-2(1H)-ones as a novel class of selective A3 adenosine receptor antagonists
Future Medicinal Chemistry, Vol. 7, Núm. 11, pp. 1373-1380
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Sol-gel entrapped Cu in a silica matrix: An efficient heterogeneous nanocatalyst for Huisgen and Ullmann intramolecular coupling reactions
Applied Catalysis A: General, Vol. 502, pp. 86-95
2014
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Structure-based design of new KSP-Eg5 inhibitors assisted by a targeted multicomponent reaction
ChemBioChem, Vol. 15, Núm. 10, pp. 1471-1480
2013
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Copper-catalyzed huisgen 1,3-dipolar cycloaddition under oxidative conditions: Polymer-assisted assembly of 4-acyl-1-substituted-1,2,3-triazoles
Journal of Organic Chemistry, Vol. 78, Núm. 13, pp. 6540-6549
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Discovery of 3,4-dihydropyrimidin-2(1 H)-ones as a novel class of potent and selective A2B adenosine receptor antagonists
ACS Medicinal Chemistry Letters, Vol. 4, Núm. 11, pp. 1031-1036
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Multicomponent assembly of diverse pyrazin-2(1 H)-one chemotypes
Journal of Organic Chemistry, Vol. 78, Núm. 9, pp. 4402-4409
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Selective and potent adenosine A3 receptor antagonists by methoxyaryl substitution on the N-(2,6-diarylpyrimidin-4-yl)acetamide scaffold
European Journal of Medicinal Chemistry, Vol. 59, pp. 235-242
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Three-component assembly of structurally diverse 2-aminopyrimidine-5- carbonitriles
ACS Combinatorial Science, Vol. 15, Núm. 7, pp. 370-378
2012
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Discovery and preliminary SAR of 5-arylidene-2,2-dimethyl-1,3-dioxane-4,6- diones as platelet aggregation inhibitors
Combinatorial Chemistry and High Throughput Screening, Vol. 15, Núm. 7, pp. 551-554
2011
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Convergent assembly of structurally diverse quinazolines
Organic and Biomolecular Chemistry, Vol. 9, Núm. 2, pp. 351-357
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Pyrimidine derivatives as potent and selective A3 adenosine receptor antagonists
Journal of Medicinal Chemistry, Vol. 54, Núm. 2, pp. 457-471
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Silica-supported aluminum chloride-assisted solution phase synthesis of pyridazinone-based antiplatelet agents
ACS Combinatorial Science, Vol. 13, Núm. 1, pp. 7-12