Thromboelastographic Analsysis of Hemostatic Abnormalities in Domestic Animals

  1. Vilar Saavedra, Paulo
Supervised by:
  1. Nuria V. Alemañ Posadas Director

Defence university: Universidade de Santiago de Compostela

Fecha de defensa: 02 October 2020

Committee:
  1. Vilma Yuzbasiyan-Gurkan Chair
  2. Germán Santamarina Pernas Secretary
  3. Josep Pastor Milán Committee member
Department:
  1. Department of Anatomy, Animal Production and Clinical Veterinary Science

Type: Thesis

Teseo: 636873 DIALNET lock_openMINERVA editor

Abstract

We evaluated the canine and equine hemostasis in a variety of pathophysiological conditions. We hypothesized that dogs with carcinoma and visceral hemangiosarcoma (vHSA) would have coagulopathies. Likewise, coagulopaties would be observed in Retired Racing Greyhounds (RRG) undergoing surgery and in horses with intestinal pathologies among others. Our objective was to describe hemostatic abnormalities by using Thromboelastography (TEG). Results described hypercoagulability and Disseminated Intravascular Coagulopathy in dogs with carcinomas and vHSA respectively. RRG trend to hypocoagulate compared to other breeds. Hemostatic alterations resulting in vascular fibrin deposits in horses do not correlate with TEG parameters nor with fibrin detection methods (i.e, PTAH, IHC)