Centro de Investigación en Medicina Molecular e Enfermidades Crónicas (CIMUS)
Centro singular
Technical University Munich
Múnich, AlemaniaPublicacións en colaboración con investigadores/as de Technical University Munich (29)
2024
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Dual and Triple Incretin-Based Co-agonists: Novel Therapeutics for Obesity and Diabetes
DIABETES THERAPY, Vol. 15, Núm. 5, pp. 1069-1084
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Immunomodulatory leptin receptor+ sympathetic perineurial barrier cells protect against obesity by facilitating brown adipose tissue thermogenesis
Immunity, Vol. 57, Núm. 1, pp. 141-152.e5
2023
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A second update on mapping the human genetic architecture of COVID-19
Nature
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Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1
Cell Metabolism, Vol. 35, Núm. 3, pp. 438-455.e7
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Gut hormone co-agonists for the treatment of obesity: from bench to bedside
Nature Metabolism, Vol. 5, Núm. 6, pp. 933-944
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High-calorie diets uncouple hypothalamic oxytocin neurons from a gut-to-brain satiation pathway via κ-opioid signaling
Cell Reports, Vol. 42, Núm. 10
2022
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Diet triggers specific responses of hypothalamic astrocytes in time and region dependent manner
GLIA, Vol. 70, Núm. 11, pp. 2062-2078
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Novel genes and sex differences in COVID-19 severity
Human molecular genetics, Vol. 31, Núm. 22, pp. 3789-3806
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Trip13 Depletion in Liver Cancer Induces a Lipogenic Response Contributing to Plin2-Dependent Mitotic Cell Death
Advanced Science, Vol. 9, Núm. 29
2020
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Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity
Journal of Clinical Investigation, Vol. 130, Núm. 11, pp. 6093-6108
2019
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Functional identity of hypothalamic melanocortin neurons depends on Tbx3
Nature Metabolism, Vol. 1, Núm. 2, pp. 222-235
2018
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Ghrelin and LEAP-2: Rivals in Energy Metabolism
Trends in Pharmacological Sciences, Vol. 39, Núm. 8, pp. 685-694
2017
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Association analysis identifies 65 new breast cancer risk loci
Nature, Vol. 551, Núm. 7678, pp. 92-94
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Current Understanding of the Hypothalamic Ghrelin Pathways Inducing Appetite and Adiposity
Trends in Neurosciences, Vol. 40, Núm. 3, pp. 167-180
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Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer
Nature Genetics, Vol. 49, Núm. 12, pp. 1767-1778
2016
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Comparison of international normalized ratio audit parameters in patients enrolled in GARFIELD-AF and treated with vitamin K antagonists
British Journal of Haematology, Vol. 174, Núm. 4, pp. 610-623
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Sequence variation between 462 human individuals fine-tunes functional sites of RNA processing
Scientific Reports, Vol. 6
2015
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Does sex affect anticoagulant use for stroke prevention in nonvalvular atrial fibrillation?: The prospective global anticoagulant registry in the FIELD-Atrial Fibrillation
Circulation: Cardiovascular Quality and Outcomes, Vol. 8, pp. S12-S20
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Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk
Human Molecular Genetics, Vol. 24, Núm. 5, pp. 1478-1492
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Ghrelin
Molecular Metabolism, Vol. 4, Núm. 6, pp. 437-460