Centro de Investigación en Medicina Molecular e Enfermidades Crónicas (CIMUS)
Centro singular
Centro de Investigación Cooperativa en Biotecnología
Zamudio, España
Publicacións en colaboración con investigadores/as de Centro de Investigación Cooperativa en Biotecnología (75)
2025
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Cofactors facilitate bona fide prion misfolding in vitro but are not necessary for the infectivity of recombinant murine prions
PLoS Pathogens, Vol. 21, Núm. 1
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Conservation of strain properties of bank vole-adapted chronic wasting disease in the absence of glycosylation and membrane anchoring
Neurobiology of Disease, Vol. 210
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Effect of primary structural variation on cervid prion protein in flexibility, stability, and spontaneous misfolding propensity
Neurobiology of Disease, Vol. 213
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Metabolic dysfunction-associated steatotic liver disease alters brain function and behavior: Insights from liver-targeted siRNA therapy
Science advances, Vol. 11, Núm. 43, pp. eady9758
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Modulatory effects of CNNM4 on protein- l -isoaspartyl- O -methyltransferase repair function during alcohol-induced hepatic damage
Hepatology, Vol. 82, Núm. 2, pp. 388-404
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NEDDylation Regulates CD8+ T-cell Metabolism and Antitumor Immunity
Cancer immunology research, Vol. 13, Núm. 7, pp. 1004-1021
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SUMOylation of the lysine-less tumor suppressor p14ARF counters ubiquitylation-dependent degradation
Cell Death and Disease, Vol. 16, Núm. 1
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Spontaneous generation of diverse recombinant prion strains: sulfated glycan cofactors facilitate strain emergence but do not determine specific strain properties
Acta Neuropathologica Communications , Vol. 13, Núm. 1
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Trajectory analysis of hepatic stellate cell differentiation reveals metabolic regulation of cell commitment and fibrosis
Nature Communications , Vol. 16, Núm. 1
2024
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Neddylation inhibition prevents acetaminophen-induced liver damage by enhancing the anabolic cardiolipin pathway
Cell Reports Medicine, Vol. 5, Núm. 7
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Proceedings of the 5th Meeting of Translational Hepatology, organized by the Spanish Association for the Study of the Liver (AEEH)
Gastroenterologia y Hepatologia
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ProteoCure: A European network to fine-tune the proteome
Biochimie
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SUMOylation modulates eIF5A activities in both yeast and pancreatic ductal adenocarcinoma cells
Cellular and Molecular Biology Letters, Vol. 29, Núm. 1
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The lipopolysaccharide-TLR4 axis regulates hepatic glutaminase 1 expression promoting liver ammonia build-up as steatotic liver disease progresses to steatohepatitis
Metabolism: Clinical and Experimental, Vol. 158
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p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway
Cell Reports Medicine, Vol. 5, Núm. 2
2023
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A second update on mapping the human genetic architecture of COVID-19
Nature
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A tetracationic porphyrin with dual anti-prion activity
iScience, Vol. 26, Núm. 9
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Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression
Hepatology, Vol. 77, Núm. 5, pp. 1654-1669
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Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting
Cell Metabolism, Vol. 35, Núm. 8, pp. 1373-1389.e8
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Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function
Molecular Metabolism, Vol. 75