Centro de Investigación en Medicina Molecular e Enfermidades Crónicas (CIMUS)
Centro singular
Basque Research and Technology Alliance
Mendaro, España
2025
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A Machine-Learning Approach Identifies Rejuvenating Interventions in the Human Brain
Advanced Science, Vol. 12, Núm. 37
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Cofactors facilitate bona fide prion misfolding in vitro but are not necessary for the infectivity of recombinant murine prions
PLoS Pathogens, Vol. 21, Núm. 1
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Conservation of strain properties of bank vole-adapted chronic wasting disease in the absence of glycosylation and membrane anchoring
Neurobiology of Disease, Vol. 210
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Effect of primary structural variation on cervid prion protein in flexibility, stability, and spontaneous misfolding propensity
Neurobiology of Disease, Vol. 213
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Spontaneous generation of diverse recombinant prion strains: sulfated glycan cofactors facilitate strain emergence but do not determine specific strain properties
Acta Neuropathologica Communications , Vol. 13, Núm. 1
2024
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Controlling the protein corona of polymeric nanocapsules: effect of polymer shell on protein adsorption
Drug Delivery and Translational Research, Vol. 14, Núm. 4, pp. 918-933
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Engineering hyaluronic acid-based nanoassemblies for monoclonal antibody delivery – design, characterization, and biological insights
Nano Research, Vol. 17, Núm. 10, pp. 9111-9125
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Global and single-nucleotide resolution detection of 7-methylguanosine in RNA
RNA Biology, Vol. 21, Núm. 1, pp. 1-18
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Nanotechnology-assisted intracellular delivery of antibody as a precision therapy approach for KRAS-driven tumors
Journal of Controlled Release, Vol. 373, pp. 277-292
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Neddylation orchestrates the complex transcriptional and posttranscriptional program that drives Schwann cell myelination
Science Advances, Vol. 10, Núm. 15
2023
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METTL1 promotes tumorigenesis through tRNA-derived fragment biogenesis in prostate cancer
Molecular cancer, Vol. 22, Núm. 1, pp. 119
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N7-methylguanosine methylation of tRNAs regulates survival to stress in cancer
Oncogene, Vol. 42, Núm. 43, pp. 3169-3181
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The outcome of boosting mitochondrial activity in alcohol-associated liver disease is organ-dependent
Hepatology (Baltimore, Md.), Vol. 78, Núm. 3, pp. 878-895
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Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation
Acta Neuropathologica Communications, Vol. 11, Núm. 1
2022
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Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model
Acta Neuropathologica Communications, Vol. 10, Núm. 1
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Methionine adenosyltransferase 1a antisense oligonucleotides activate the liver-brown adipose tissue axis preventing obesity and associated hepatosteatosis
Nature Communications, Vol. 13, Núm. 1
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Neddylation tunes peripheral blood mononuclear cells immune response in COVID-19 patients
Cell Death Discovery, Vol. 8, Núm. 1
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The spike of SARS-CoV-2 promotes metabolic rewiring in hepatocytes
Communications Biology, Vol. 5, Núm. 1