Molecular Medicine and Chronic Diseases Research Center (CIMUS)
Singular centre
MARCOS
FERNANDEZ FONDEVILA
Researcher in the period 2022-2024
2025
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Activation of intestinal endogenous retroviruses by alcohol exacerbates liver disease
Journal of Clinical Investigation, Vol. 135, Núm. 13
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Mitochondrial antiviral signaling protein enhances MASLD progression through the ERK/TNFα/NFκβ pathway
Hepatology, Vol. 81, Núm. 5, pp. 1535-1552
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Targeted inhibition of pathobiont virulence factor mitigates alcohol-associated liver disease
Cell Host and Microbe, Vol. 33, Núm. 6, pp. 957-972.e6
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Towards more consistent models and consensual terminology in preclinical research for steatotic liver disease
Journal of Hepatology, Vol. 82, Núm. 4, pp. 760-766
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mAChR4 suppresses liver disease via GAP-induced antimicrobial immunity
Nature, Vol. 646, Núm. 8083, pp. 180-189
2024
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Faecal proteomics links neutrophil degranulation with mortality in patients with alcohol-associated hepatitis
Gut, Vol. 74, Núm. 1, pp. 103-115
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Inhibition of hepatic p63 ameliorates steatohepatitis with fibrosis in mice
Molecular Metabolism, Vol. 85
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The central role of the gut microbiota in the pathophysiology and management of type 2 diabetes
Cell Host and Microbe, Vol. 32, Núm. 8, pp. 1280-1300
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The lipopolysaccharide-TLR4 axis regulates hepatic glutaminase 1 expression promoting liver ammonia build-up as steatotic liver disease progresses to steatohepatitis
Metabolism: Clinical and Experimental, Vol. 158
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p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway
Cell Reports Medicine, Vol. 5, Núm. 2
2023
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Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting
Cell Metabolism, Vol. 35, Núm. 8, pp. 1373-1389.e8
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Hepatic p63 regulates glucose metabolism by repressing SIRT1
Gut, Vol. 72, Núm. 3, pp. 472-483
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Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function
Molecular Metabolism, Vol. 75
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Intestinal clock modulates rhythmic hepatic metabolism
Journal of Hepatology
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Neddylation of phosphoenolpyruvate carboxykinase 1 controls glucose metabolism
Cell Metabolism, Vol. 35, Núm. 9, pp. 1630-1645.e5
2022
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Inhibition of ATG3 ameliorates liver steatosis by increasing mitochondrial function
Journal of Hepatology, Vol. 76, Núm. 1, pp. 11-24
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Inhibition of carnitine palmitoyltransferase 1A in hepatic stellate cells protects against fibrosis
Journal of Hepatology, Vol. 77, Núm. 1, pp. 15-28
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O-GlcNAcylation: A Sweet Hub in the Regulation of Glucose Metabolism in Health and Disease
Frontiers in Endocrinology, Vol. 13
2021
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Metabolic Landscape of the Mouse Liver by Quantitative 31P Nuclear Magnetic Resonance Analysis of the Phosphorome
Hepatology, Vol. 74, Núm. 1, pp. 148-163
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O-GlcNAcylated p53 in the liver modulates hepatic glucose production
Nature Communications, Vol. 12, Núm. 1