Publikationen in Zusammenarbeit mit Forschern von Centro Nacional de Biotecnología (16)

2024

  1. SUMOylation modulates eIF5A activities in both yeast and pancreatic ductal adenocarcinoma cells

    Cellular and Molecular Biology Letters, Vol. 29, Núm. 1

2023

  1. Quinate-based ligands for irreversible inactivation of the bacterial virulence factor DHQ1 enzyme—A molecular insight †

    Frontiers in Molecular Biosciences, Vol. 10

2021

  1. Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture

    Nature Communications, Vol. 12, Núm. 1

2020

  1. Self-Immolation of a Bacterial Dehydratase Enzyme by its Epoxide Product

    Chemistry - A European Journal, Vol. 26, Núm. 36, pp. 8035-8044

2019

  1. Hydroxylammonium derivatives for selective active-site lysine modification in the anti-virulence bacterial target DHQ1 enzyme

    Organic Chemistry Frontiers, Vol. 6, Núm. 17, pp. 3127-3135

2015

  1. Chemical Modification of a Dehydratase Enzyme Involved in Bacterial Virulence by an Ammonium Derivative: Evidence of its Active Site Covalent Adduct

    Journal of the American Chemical Society, Vol. 137, Núm. 29, pp. 9333-9343

  2. Irreversible covalent modification of type i dehydroquinase with a stable Schiff base

    Organic and Biomolecular Chemistry, Vol. 13, Núm. 3, pp. 706-716

2014

  1. Exploring the water-binding pocket of the type II dehydroquinase enzyme in the structure-based design of inhibitors

    Journal of Medicinal Chemistry, Vol. 57, Núm. 8, pp. 3494-3510

  2. Insights into substrate binding and catalysis in bacterial type i dehydroquinase

    Biochemical Journal, Vol. 462, Núm. 3, pp. 415-424

2013

  1. Design, synthesis, and structural analysis of turn modified cyclo-(αβ3αβ2α)2 peptide derivatives toward crystalline hexagon-shaped cationic nanochannel assemblies

    Crystal Growth and Design, Vol. 13, Núm. 10, pp. 4355-4367

  2. Mechanistic basis of the inhibition of type II dehydroquinase by (2 S)- and (2 R)-2-benzyl-3-dehydroquinic acids

    ACS Chemical Biology, Vol. 8, Núm. 3, pp. 568-577

  3. Mycobacterium tuberculosis shikimate kinase inhibitors: Design and simulation studies of the catalytic turnover

    Journal of the American Chemical Society, Vol. 135, Núm. 33, pp. 12366-12376

2011

  1. A prodrug approach for improving antituberculosis activity of potent mycobacterium tuberculosis type II dehydroquinase inhibitors

    Journal of Medicinal Chemistry, Vol. 54, Núm. 17, pp. 6063-6084

  2. Tetrahydrobenzothiophene Derivatives: Conformationally Restricted Inhibitors of TypeII Dehydroquinase

    ChemMedChem, Vol. 6, Núm. 2, pp. 266-272

2009

  1. α,γ-Peptide nanotube templating of one-dimensional parallel fullerene arrangements

    Journal of the American Chemical Society, Vol. 131, Núm. 32, pp. 11335-11337

2003

  1. Evidence that avian reovirus σA protein is an inhibitor of the double-stranded RNA-dependent protein kinase

    Journal of General Virology, Vol. 84, Núm. 6, pp. 1629-1639