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RAMON
SOTO OTERO
Ad honorem Emeritus professor
Publications (67) RAMON SOTO OTERO publications
2024
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Copper Overload Increased Rat Striatal Levels of Both Dopamine and Its Main Metabolite Homovanillic Acid in Extracellular Fluid
International Journal of Molecular Sciences, Vol. 25, Núm. 15
2023
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Assessment of Oxidative Stress Markers in Hypertensive Patients under the Use of Renin-Angiotensin-Aldosterone Blockers
Antioxidants, Vol. 12, Núm. 4
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Implications of Inflammatory and Oxidative Stress Markers in the Attenuation of Nocturnal Blood Pressure Dipping
Journal of Clinical Medicine, Vol. 12, Núm. 4
2022
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Assessment of oxidative stress markers in elderly patients with SARS-CoV-2 infection and potential prognostic implications in the medium and long term
PloS one, Vol. 17, Núm. 10, pp. e0268871
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Correlation between Blunted Nocturnal Decrease in Diastolic Blood Pressure and Oxidative Stress: An Observational Study
Antioxidants, Vol. 11, Núm. 12
2019
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Copper Increases Brain Oxidative Stress and Enhances the Ability of 6-Hydroxydopamine to Cause Dopaminergic Degeneration in a Rat Model of Parkinson’s Disease
Molecular Neurobiology, Vol. 56, Núm. 4, pp. 2845-2854
2017
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Copper increases the ability of 6-hydroxydopamine to generate oxidative stress and the ability of ascorbate and glutathione to potentiate this effect: potential implications in Parkinson's disease
Journal of Neurochemistry, Vol. 141, Núm. 5, pp. 738-749
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Effects of Aluminium on Rat Brain Mitochondria Bioenergetics: an In vitro and In vivo Study
Molecular Neurobiology, Vol. 54, Núm. 1, pp. 563-570
2016
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8-Aminomethyl-7-hydroxy-4-methylcoumarins as Multitarget Leads for Alzheimer's Disease
ChemistrySelect, Vol. 1, Núm. 11, pp. 2742-2749
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Exploring Basic Tail Modifications of Coumarin-Based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-Soluble, Brain-Permeant Neuroprotective Multitarget Agents
Journal of Medicinal Chemistry, Vol. 59, Núm. 14, pp. 6791-6806
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Mitochondrial angiotensin receptors in dopaminergic neurons. Role in cell protection and aging-related vulnerability to neurodegeneration
Cell Death and Disease, Vol. 7, Núm. 10
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Searching for multi-targeting neurotherapeutics against Alzheimer's: Discovery of potent AChE-MAO B inhibitors through the decoration of the 2H-Chromen-2-one structural motif
Molecules, Vol. 21, Núm. 3
2015
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In silico design of novel 2H-chromen-2-one derivatives as potent and selective MAO-B inhibitors
European Journal of Medicinal Chemistry, Vol. 89, pp. 98-105
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Structure-Based Design and Optimization of Multitarget-Directed 2 H -Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases
Journal of Medicinal Chemistry, Vol. 58, Núm. 14, pp. 5561-5578
2013
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A simple method for isolating rat brain mitochondria with high metabolic activity: Effects of EDTA and EGTA
Journal of Neuroscience Methods, Vol. 213, Núm. 1, pp. 39-42
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Discovery, biological evaluation, and structure-activity and -selectivity relationships of 6′-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N- methylacetamides, a novel class of potent and selective monoamine oxidase inhibitors
Journal of Medicinal Chemistry, Vol. 56, Núm. 6, pp. 2651-2664
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Fine molecular tuning at position 4 of 2H-chromen-2-one derivatives in the search of potent and selective monoamine oxidase B inhibitors
European Journal of Medicinal Chemistry, Vol. 70, pp. 723-739
2012
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2-Benzazepine nitrones protect dopaminergic neurons against 6-hydroxydopamine-induced oxidative toxicity
Archiv der Pharmazie, Vol. 345, Núm. 8, pp. 598-609
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Differential toxicity of 6-hydroxydopamine in SH-SY5Y human neuroblastoma cells and rat brain mitochondria: Protective role of catalase and superoxide dismutase
Neurochemical Research, Vol. 37, Núm. 10, pp. 2150-2160
2011
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Antioxidant properties of dimethyl sulfoxide and its viability as a solvent in the evaluation of neuroprotective antioxidants
Journal of Pharmacological and Toxicological Methods, Vol. 63, Núm. 2, pp. 209-215