MANUEL MARIA
PAZ CASTAÑAL
Senior university lecturer
Publications (41) MANUEL MARIA PAZ CASTAÑAL publications
2023
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Facile generation of surface diversity in gold nanoparticles
Journal of Colloid and Interface Science, Vol. 641, pp. 719-728
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Insight Into Factors Governing Formation, Synthesis and Stereochemical Configuration of DNA Adducts Formed by Mitomycins
Chemical Record, Vol. 23, Núm. 1
2020
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Synthesis of Oligonucleotides containing the cis-Interstrand Crosslink Produced by Mitomycins in their Reaction with DNA
Chemistry - A European Journal, Vol. 26, Núm. 55, pp. 12570-12578
2019
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Size-Dependent Transport and Cytotoxicity of Mitomycin-Gold Nanoparticle Conjugates in 2D and 3D Mammalian Cell Models
Bioconjugate Chemistry, Vol. 30, Núm. 1, pp. 242-252
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Synthesis of Mitomycin C and decarbamoylmitomycin C N6 deoxyadenosine-adducts
Bioorganic Chemistry, Vol. 92
2018
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Interdependent Sequence Selectivity and Diastereoselectivity in the Alkylation of DNA by Decarbamoylmitomycin C
Chemistry - A European Journal, Vol. 24, Núm. 50, pp. 13278-13289
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Isolation and Rationale for the Formation of Isomeric Decarbamoylmitomycin C- N6-deoxyadenosine Adducts in DNA
Chemical Research in Toxicology, Vol. 31, Núm. 8, pp. 762-771
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Sequence-Dependent Diastereospecific and Diastereodivergent Crosslinking of DNA by Decarbamoylmitomycin C
Chemistry - A European Journal, Vol. 24, Núm. 23, pp. 6030-6035
2017
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Acetone promoted 1,4-migration of an alkoxycarbonyl group on a syn-1,2-diamine
Tetrahedron Letters, Vol. 58, Núm. 7, pp. 597-601
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Aditivos acidulantes y reguladores del pH
Aditivos alimentarios (Dextra), pp. 241-266
2016
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Synthesis of Mitomycin C and Decarbamoylmitomycin C N2 deoxyguanosine-adducts
Bioorganic Chemistry, Vol. 65, pp. 90-99
2013
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Reductive activation of mitomycins A and C by vitamin C
Bioorganic Chemistry, Vol. 48, Núm. 1, pp. 1-7
2012
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A new mechanism of action for the anticancer drug Mitomycin C: Mechanism-based inhibition of thioredoxin reductase
Chemical Research in Toxicology, Vol. 25, Núm. 7, pp. 1502-1511
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Synthesis of a major mitomycin C DNA adduct via a triaminomitosene
Bioorganic and Medicinal Chemistry Letters, Vol. 22, Núm. 23, pp. 7198-7200
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The molecular toxicology of mitomycin C
Advances in Molecular Toxicology (Elsevier B.V.), pp. 243-299
2010
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Cross-linking of dithiols by mitomycin C
Chemical Research in Toxicology, Vol. 23, Núm. 8, pp. 1384-1392
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Reaction of reductively activated mitomycin C with aqueous bicarbonate: Isolation and characterization of an oxazolidinone derivative of cis-1-hydroxy-2,7-diaminomitosene
Bioorganic and Medicinal Chemistry Letters, Vol. 20, Núm. 1, pp. 31-34
2009
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ORGN 19-Synthesis of two stereoisomeric deoxyribonucleoside adducts of mitomycin C
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
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Reductive activation of mitomycin C by thiols: Kinetics, mechanism, and biological implications
Chemical Research in Toxicology, Vol. 22, Núm. 10, pp. 1663-1668
2008
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Antitumour Antibiotics
Anticancer Therapeutics (John Wiley & Sons, Ltd), pp. 111-131