JUAN ANDRES
PARGA MARTIN
Profesor titular de universidade
Publicacións (27) Publicacións de JUAN ANDRES PARGA MARTIN
2024
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Non-HLA angiotensin-type-1 receptor autoantibodies mediate the long-term loss of grafted neurons in Parkinson’s disease models
Stem Cell Research and Therapy, Vol. 15, Núm. 1
2023
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Combined cell-based therapy strategies for the treatment of Parkinson's disease: Focus on mesenchymal stromal cells
Neural Regeneration Research, Vol. 18, Núm. 3, pp. 478-484
2022
2021
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Dopamine regulates adult neurogenesis in the ventricular-subventricular zone via dopamine D3 angiotensin type 2 receptor interactions
Stem Cells, Vol. 39, Núm. 12, pp. 1778-1794
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Dose-dependent effect of mesenchymal stromal cells co-grafted with dopaminergic neurons in a Parkinson's disease rat model
Journal of Cellular and Molecular Medicine, Vol. 25, Núm. 20, pp. 9884-9889
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Nrf2 activation and downstream effects: Focus on parkinson’s disease and brain angiotensin
Antioxidants, Vol. 10, Núm. 11
2019
2018
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Angiotensin II induces oxidative stress and upregulates neuroprotective signaling from the NRF2 and KLF9 pathway in dopaminergic cells
Free Radical Biology and Medicine, Vol. 129, pp. 394-406
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Data on the effect of Angiotensin II and 6-hydroxydopamine on reactive oxygen species production, antioxidant gene expression and viability of different neuronal cell lines
Data in Brief
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Paracrine and Intracrine Angiotensin 1-7/Mas Receptor Axis in the Substantia Nigra of Rodents, Monkeys, and Humans
Molecular Neurobiology, Vol. 55, Núm. 7, pp. 5847-5867
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Prostaglandin EP2 Receptors Mediate Mesenchymal Stromal Cell-Neuroprotective Effects on Dopaminergic Neurons
Molecular Neurobiology, Vol. 55, Núm. 6, pp. 4763-4776
2016
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Effects of rho kinase inhibitors on grafts of dopaminergic cell precursors in a rat model of Parkinson’s disease
Stem Cells Translational Medicine, Vol. 5, Núm. 6, pp. 804-815
2013
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Derivation and Expansion Using Only Small Molecules of Human Neural Progenitors for Neurodegenerative Disease Modeling
PLoS ONE, Vol. 8, Núm. 3
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Discovery of neuritogenic compound classes inspired by natural products
Angewandte Chemie - International Edition, Vol. 52, Núm. 36, pp. 9576-9581
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Highly enantioselective catalytic synthesis of neurite growth-promoting secoyohimbanes
Chemistry and Biology, Vol. 20, Núm. 4, pp. 500-509
2012
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Discovery of inhibitors of microglial neurotoxicity acting through multiple mechanisms using a stem-cell-based phenotypic assay
Cell Stem Cell, Vol. 11, Núm. 5, pp. 620-632
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Mitochondrial ATP-sensitive potassium channels enhance angiotensin-induced oxidative damage and dopaminergic neuron degeneration. Relevance for aging-associated susceptibility to Parkinson's disease
Age, Vol. 34, Núm. 4, pp. 863-880
2010
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Effect of inhibitors of NADPH oxidase complex and mitochondrial ATP-sensitive potassium channels on generation of dopaminergic neurons from neurospheres of mesencephalic precursors
Developmental Dynamics, Vol. 239, Núm. 12, pp. 3247-3259
2009
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The mitochondrial ATP-sensitive potassium channel blocker 5-hydroxydecanoate inhibits toxicity of 6-hydroxydopamine on dopaminergic neurons
Neurotoxicity Research, Vol. 15, Núm. 1, pp. 82-95
2008
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Brain angiotensin enhances dopaminergic cell death via microglial activation and NADPH-derived ROS
Neurobiology of Disease, Vol. 31, Núm. 1, pp. 58-73