Publicacións (267) Publicacións de María Isabel Loza García

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2025

  1. Copper(II) Cyclopeptides with High ROS-Mediated Cytotoxicity

    Bioconjugate Chemistry, Vol. 36, Núm. 3, pp. 500-509

  2. Design, Synthesis, and Evaluation of a New Fluorescent Ligand for the M2 Muscarinic Acetylcholine Receptor

    ACS Medicinal Chemistry Letters

  3. Design, Synthesis, and Evaluation of a New Fluorescent Ligand for the M2 Muscarinic Acetylcholine Receptor

    ACS Medicinal Chemistry Letters, Vol. 16, Núm. 4, pp. 552-559

  4. Discovery of (3-Phenylcarbamoyl-3,4-dihydro-2H-pyrrol-2-yl)phosphonates as Imidazoline I2 Receptor Ligands with Anti-Alzheimer and Analgesic Properties

    Journal of Medicinal Chemistry, Vol. 68, Núm. 3, pp. 2551-2573

  5. Discovery of N-substituted-2-((arylethyl)amino)-2-(2-methoxyphenyl) acetamides: A novel family of antiplatelet agents

    Biomedicine and Pharmacotherapy, Vol. 186

  6. Exploring Trisubstituted adenine derivatives as adenosine A1 receptor ligands with antagonist activity: Synthesis, biological evaluation and molecular modelling

    Bioorganic Chemistry, Vol. 159

2024

  1. 2-Aryladenine Derivatives as a Potent Scaffold for Adenosine Receptor Antagonists: The 6-Morpholino Derivatives

    Molecules, Vol. 29, Núm. 11

  2. Design, synthesis and validation of a new Crimped Head-Piece for DNA-Encoded libraries generation

    Bioorganic and Medicinal Chemistry, Vol. 99

  3. Effect of Bulky N-Dibenzofuranylmethyl Substitution on the 5-HT2 Receptor Affinity and Efficacy of a Psychedelic Phenethylamine

    ACS Chemical Neuroscience, Vol. 15, Núm. 3, pp. 608-616

  4. Efficacy of SIGMAR1-based therapy in the early treatment of confirmed mild symptomatic COVID-19 patients

    Journal of Infection

  5. Exploring Biginelli-based scaffolds as A2B adenosine receptor antagonists: Unveiling novel structure-activity relationship trends, lead compounds, and potent colorectal anticancer agents

    Biomedicine and Pharmacotherapy, Vol. 173

  6. G protein-specific mechanisms in the serotonin 5-HT2A receptor regulate psychosis-related effects and memory deficits

    Nature communications, Vol. 15, Núm. 1, pp. 4307

  7. High-Throughput DNA-Encoded Libraries Affinity Selection Platform for Binder Identification with Solid Support Protein Immobilization

    Assay and Drug Development Technologies, Vol. 22, Núm. 4, pp. 192-202

  8. High-throughput nephelometry methodology for qualitative determination of aqueous solubility of chemical libraries

    SLAS Discovery, Vol. 29, Núm. 3

  9. In vitro models for neuropathic pain phenotypic screening in brain therapeutics

    Pharmacological Research, Vol. 202

  10. N-Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as Fluorescent Probes to Detect Microglia Activation through the Imaging of Cannabinoid Receptor Subtype 2 (CB2R)

    Journal of Medicinal Chemistry, Vol. 67, Núm. 13, pp. 11003-11023

  11. Nanoemulsions and nanocapsules as carriers for the development of intranasal mRNA vaccines

    Drug Delivery and Translational Research, Vol. 14, Núm. 8, pp. 2046-2061

  12. Stepwise Structural Simplification of the Dihydroxyanthraquinone Moiety of a Multitarget Rhein-Based Anti-Alzheimer Lead to Improve Drug Metabolism and Pharmacokinetic Properties

    Pharmaceutics, Vol. 16, Núm. 8

2023

  1. 8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies

    European Journal of Medicinal Chemistry, Vol. 248

  2. A Robust and Efficient FRET-Based Assay for Cannabinoid Receptor Ligands Discovery

    Molecules, Vol. 28, Núm. 24