María Isabel
Loza García
Catedrática de universidad
![Foto de María Isabel](/img/uploaded/71A9B508C79AFAB78E38ABD10B96C498.jpg)
![Foto de Universitat de Barcelona](/img/noimage_org.png)
Universitat de Barcelona
Barcelona, EspañaPublicaciones en colaboración con investigadores/as de Universitat de Barcelona (28)
2024
2023
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A Robust and Efficient FRET-Based Assay for Cannabinoid Receptor Ligands Discovery
Molecules, Vol. 28, Núm. 24
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Pharmacological insights emerging from the characterization of a large collection of synthetic cannabinoid receptor agonists designer drugs
Biomedicine and Pharmacotherapy, Vol. 164
2022
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A New Family of Subnanomolar inhibitors of Soluble Epoxide Hydrolase
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 36
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Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 236
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Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease
Journal of Medicinal Chemistry, Vol. 65, Núm. 6, pp. 4909-4925
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Insights into the Pharmacokinetics and In Vitro Cell‐Based Studies of the Imidazoline I2 Receptor Ligand B06
International Journal of Molecular Sciences, Vol. 23, Núm. 10
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Soluble Epoxide Hydrolase Inhibitors: Design, Synthesis, in vitro Profiling and in vivo Evaluation in Murine Models of Pain
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 36
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Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors
Journal of medicinal chemistry, Vol. 65, Núm. 20, pp. 13660-13680
2021
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2-(Piperidin-4-yl)acetamides as Potent Inhibitors of Soluble Epoxide Hydrolase with Anti-Inflammatory Activity
Pharmaceuticals, Vol. 14, Núm. 12
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Benzofuranyl-2-imidazoles as imidazoline I2 receptor ligands for Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 222
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From the Design to the in Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis
Journal of Medicinal Chemistry, Vol. 64, Núm. 9, pp. 5429-5446
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From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects
European Journal of Medicinal Chemistry, Vol. 225
2020
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2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Model of Acute Pancreatitis
Journal of medicinal chemistry, Vol. 63, Núm. 17, pp. 9237-9257
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A novel NMDA receptor antagonist protects against cognitive decline presented by senescent mice
Pharmaceutics, Vol. 12, Núm. 3
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Bicyclic α-Iminophosphonates as High Affinity Imidazoline I2 Receptor Ligands for Alzheimer's Disease
Journal of Medicinal Chemistry, Vol. 63, Núm. 7, pp. 3610-3633
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Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6
Journal of Medicinal Chemistry, Vol. 63, Núm. 17, pp. 9360-9390
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Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer’s Disease
Neurotherapeutics, Vol. 17, Núm. 4, pp. 1825-1835
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Pharmacology and preclinical validation of a novel anticancer compound targeting PEPCK-M
Biomedicine and Pharmacotherapy, Vol. 121
2019
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A New Model of Sensorial Neuron-Like Cells for HTS of Novel Analgesics for Neuropathic Pain
SLAS Discovery, Vol. 24, Núm. 2, pp. 158-168