MANUEL
FREIRE RAMA
Researcher in the period 1987-2017
Publications (39) MANUEL FREIRE RAMA publications
2017
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Prothymosin α interacts with SET, ANP32A and ANP32B and other cytoplasmic and mitochondrial proteins in proliferating cells
Archives of Biochemistry and Biophysics, Vol. 635, pp. 74-86
2016
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Comorbilidades y gravedad de la apnea del sueño. Estudio en una cohorte de pacientes portugueses
Revista de Neurologia, Vol. 62, Núm. 10, pp. 433-438
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Phosphorylation of Prothymosin α. An Approach to Its Biological Significance
Vitamins and Hormones (Academic Press Inc.), pp. 73-99
2014
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The Calcineurin Inhibitor Ascomicin Interferes with the Early Stage of the Epileptogenic Process Induced by Latrunculin A Microperfusion in Rat Hippocampus
Journal of Neuroimmune Pharmacology, Vol. 9, Núm. 5, pp. 654-667
2013
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The influence of phosphorylation of prothymosin α on its nuclear import and antiapoptotic activity
Biochemistry and Cell Biology, Vol. 91, Núm. 4, pp. 265-269
2011
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The M2-type isoenzyme of pyruvate kinase phosphorylates prothymosin α in proliferating lymphocytes
Biochimica et Biophysica Acta - Proteins and Proteomics, Vol. 1814, Núm. 2, pp. 355-365
2006
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Prothymosin α interacts with free core histones in the nucleus of dividing cells
Journal of Biochemistry, Vol. 140, Núm. 5, pp. 627-637
2003
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Prothymosin α is processed to thymosin α1 and thymosin α11 by a lysosomal asparaginyl endopeptidase
Journal of Biological Chemistry, Vol. 278, Núm. 15, pp. 13286-13293
2001
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Identification of nuclear-import and cell-cycle regulatory proteins that bind to prothymosin α
Biochemistry and Cell Biology, Vol. 79, Núm. 2, pp. 123-131
2000
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A Bioquímica no final do milenio: un século de historia
Eduga: revista galega do ensino, Núm. 28, pp. 157-174
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Properties of the protein kinase that phosphorylates prothymosin α
Molecular and Cellular Biochemistry, Vol. 208, Núm. 1-2, pp. 111-118
1997
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A 180-kDa protein kinase seems to be responsible for the phosphorylation of prothymosin α observed in proliferating cells
Journal of Biological Chemistry, Vol. 272, Núm. 16, pp. 10506-10513
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Interaction of prothymosin a with nucltosomhs in vitro. c diaz-jullien
FASEB Journal, Vol. 11, Núm. 9
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Partial characterization of a 38 kda protein that binds prothymosin α in proliferating cells
FASEB Journal, Vol. 11, Núm. 9
1996
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Prothymosin α binds histones in vitro and shows activity in nucleosome assembly assay
Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology, Vol. 1296, Núm. 2, pp. 219-227
1995
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Markers of T-cell differentiation and maturation in C57BL/6 and BALB/c mice and in the calf: a comparative study
Comparative Biochemistry and Physiology -- Part B: Biochemistry and, Vol. 110, Núm. 2, pp. 349-355
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The prothymosin α gene is specifically expressed in ectodermal and mesodermal regions during early postimplantation mouse embryogenesis
FEBS Letters, Vol. 359, Núm. 1, pp. 15-19
1994
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Prothymosin α and factors from calf thymic cells decrease expression of thy 1.2 antigen among small thymocs from c57BL/6 mice
Immunopharmacology and Immunotoxicology, Vol. 16, Núm. 3, pp. 403-418
1993
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Distribution of serine esterase activity in the lymphoid system of C57bl/6 mice, effect of aging on the enzymatic activity
International Journal of Biochemistry, Vol. 25, Núm. 4, pp. 551-555
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Prothymosin α is phosphorylated in proliferating stimulated cells
Journal of Biological Chemistry, Vol. 268, Núm. 7, pp. 4704-4708