Publicacións nas que colabora con Enrique Raviña Rubira (34)

2014

  1. Synthesis and biological evaluation of a series of aminoalkyl-tetralones and tetralols as dual dopamine/serotonin ligands

    European Journal of Medicinal Chemistry, Vol. 71, pp. 237-249

2011

  1. Potential atypical antipsychotics: Synthesis, binding affinity and SAR of new heterocyclic bioisosteric butyrophenone analogues as multitarget ligands

    MedChemComm, Vol. 2, Núm. 12, pp. 1194-1200

2009

  1. Synthesis and binding affinity of potential atypical antipsychotics with the tetrahydroquinazolinone motif

    Bioorganic and Medicinal Chemistry Letters, Vol. 19, Núm. 21, pp. 6059-6062

  2. Synthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D3 receptor ligands

    Bioorganic and Medicinal Chemistry Letters, Vol. 19, Núm. 6, pp. 1773-1778

2008

  1. Synthesis, binding affinity, and molecular docking analysis of new benzofuranone derivatives as potential antipsychotics

    Journal of Medicinal Chemistry, Vol. 51, Núm. 19, pp. 6085-6094

2007

  1. Multistructure 3D-QSAR studies on a series of conformationally constrained butyrophenones docked into a new homology model of the 5-HT2A receptor

    Journal of Medicinal Chemistry, Vol. 50, Núm. 14, pp. 3242-3255

  2. Synthesis and binding affinity of new pyrazole and isoxazole derivatives as potential atypical antipsychotics

    Bioorganic and Medicinal Chemistry Letters, Vol. 17, Núm. 17, pp. 4873-4877

2006

  1. QF2004B, a potential antipsychotic butyrophenone derivative with similar pharmacological properties to clozapine

    Neuropharmacology, Vol. 51, Núm. 2, pp. 251-262

  2. Synthesis and biological evaluation of new quinazoline and cinnoline derivatives as potential atypical antipsychotics

    Chemistry and Biodiversity, Vol. 3, Núm. 1, pp. 106-117

2005

  1. Synthesis and binding affinity of novel 3-aminoethyl-1-tetralones, potential atypical antipsychotics

    Bioorganic and Medicinal Chemistry Letters, Vol. 15, Núm. 12, pp. 3063-3066

2004

  1. Chemoenzymatic synthesis and binding affinity of novel (R)- and (S)-3-aminomethyl-1-tetralones, potential atypical antipsychotics

    Bioorganic and Medicinal Chemistry Letters, Vol. 14, Núm. 3, pp. 585-589

2003

  1. Conformationally constrained butyrophenones as new pharmacological tools to study 5-HT2A and 5-HT2C receptor behaviours

    European Journal of Medicinal Chemistry

  2. In vivo and in vitro pharmacological studies of a new hypotensive compound (QF0301B) in rat: Comparison with prazosin, a known α1- adrenoceptor antagonist

    Vascular Pharmacology, Vol. 40, Núm. 2, pp. 97-108

  3. Kinetic resolution of 3-hydroxymethylbenzocycloalkanols by selective asymmetric hydrogen-transfer oxidation

    Tetrahedron Asymmetry, Vol. 14, Núm. 23, pp. 3689-3696

  4. Preparation of (R)-(-)- and (S)-(+)-3-hydroxymethyl-1-tetralone tosylates, key intermediates in the synthesis of new CNS drugs, via resolution of precursors

    Tetrahedron Asymmetry, Vol. 14, Núm. 3, pp. 381-387

2002

  1. Efficient synthesis of quinazolinones as intermediates of CNS agents via inverse-electron demand Diels-Alder reaction

    Tetrahedron Letters, Vol. 43, Núm. 19, pp. 3551-3554

  2. New serotonin 5-HT2A, 5-HT2B, and 5-HT2C receptor antagonists: Synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo and heterocycloalkanones

    Journal of Medicinal Chemistry, Vol. 45, Núm. 1, pp. 54-71

  3. New synthetic approaches to CNS drugs. A straightforward, efficient synthesis of tetrahydroindol-4-ones and tetrahydroquinolin-5-ones via palladium-catalyzed oxidation of hydroxyenaminones

    Tetrahedron Letters, Vol. 43, Núm. 44, pp. 7929-7932

2000

  1. A simple, efficient method for regioselective synthesis of 7-aminomethyl-7,8-dihydro-6H-quinolin-5-ones, new potential CNS agents

    Tetrahedron Letters, Vol. 41, Núm. 50, pp. 9829-9833

  2. Butyrophenone analogues in the carbazole series as potential atypical antipsychotics: Synthesis and determination of affinities at D2, 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors

    European Journal of Medicinal Chemistry, Vol. 35, Núm. 1, pp. 83-95