Publicacións en colaboración con investigadores/as de Universidade de Lisboa (14)

2022

  1. Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry

    Journal of the American Chemical Society, Vol. 144, Núm. 12, pp. 5284-5294

2020

  1. Sequential dual site-selective protein labelling enabled by lysine modification

    Bioorganic and Medicinal Chemistry, Vol. 28, Núm. 22

  2. Surveillance of succinate dehydrogenase gene mutation carriers: Insights from a nationwide cohort

    Clinical Endocrinology, Vol. 92, Núm. 6, pp. 545-553

2019

  1. Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents

    Nature Protocols, Vol. 14, Núm. 1, pp. 86-99

  2. Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification

    ACS Central Science, Vol. 5, Núm. 8, pp. 1417-1424

  3. Lysine Bioconjugation on Native Albumin with a Sulfonyl Acrylate Reagent

    Methods in Molecular Biology (Humana Press Inc.), pp. 25-37

  4. Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine-Selective Protein Modification and Charge Modulation

    Angewandte Chemie - International Edition, Vol. 58, Núm. 20, pp. 6640-6644

2018

  1. A silicon-labelled amino acid suitable for late-stage fluorination and unexpected oxidative cleavage reactions in the preparation of a key intermediate in the Strecker synthesis

    Peptide Science, Vol. 110, Núm. 3

  2. A thioether-directed palladium-cleavable linker for targeted bioorthogonal drug decaging

    Chemical Science, Vol. 9, Núm. 17, pp. 4185-4189

  3. Chemo- and Regioselective Lysine Modification on Native Proteins

    Journal of the American Chemical Society, Vol. 140, Núm. 11, pp. 4004-4017

  4. Synthesis and Biological Evaluation of Homogeneous Thiol-Linked NHC*-Au-Albumin and -Trastuzumab Bioconjugates

    Chemistry - A European Journal, Vol. 24, Núm. 47, pp. 12250-12253

2017

  1. Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation

    Journal of the American Chemical Society, Vol. 139, Núm. 50, pp. 18365-18375

  2. Trends in therapeutic drug conjugates for bacterial diseases: a patent review

    Expert Opinion on Therapeutic Patents, Vol. 27, Núm. 2, pp. 179-189

2016

  1. Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents

    Nature Communications, Vol. 7