MARIA DE LOS ANGELES
CASTRO PEREZ
Profesora titular de universidade
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University of Eastern Finland
Kuopio, FinlandiaPublicacións en colaboración con investigadores/as de University of Eastern Finland (15)
2024
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Discovery and in vitro Evaluation of Novel Serotonin 5-HT2A Receptor Ligands Identified Through Virtual Screening
ChemMedChem, Vol. 19, Núm. 14
2023
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Development and Characterization of Novel Selective, Non-Basic Dopamine D2 Receptor Antagonists for the Treatment of Schizophrenia
Molecules, Vol. 28, Núm. 10
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Discovery of novel arylpiperazine-based DA/5-HT modulators as potential antipsychotic agents – Design, synthesis, structural studies and pharmacological profiling
European Journal of Medicinal Chemistry, Vol. 252
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Novel multi-target ligands of dopamine and serotonin receptors for the treatment of schizophrenia based on indazole and piperazine scaffolds-synthesis, biological activity, and structural evaluation
Journal of enzyme inhibition and medicinal chemistry, Vol. 38, Núm. 1, pp. 2209828
2022
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Allosteric modulation of dopamine D2L receptor in complex with Gi1 and Gi2 proteins: the effect of subtle structural and stereochemical ligand modifications
Pharmacological Reports, Vol. 74, Núm. 2, pp. 406-424
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In vitro and in vivo evaluation of antioxidant and neuroprotective properties of antipsychotic D2AAK1
Neurochemical Research, Vol. 47, Núm. 6, pp. 1778-1789
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Multitarget Derivatives of D2AAK1 as Potential Antipsychotics: The Effect of Substitution in the Indole Moiety
ChemMedChem, Vol. 17, Núm. 15
2021
2020
2019
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Synthesis, pharmacological and structural studies of 5-substituted-3-(1-arylmethyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as multi-target ligands of aminergic GPCRs
European Journal of Medicinal Chemistry, Vol. 180, pp. 673-689
2018
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Synthesis, Structural and Thermal Studies of 3-(1-Benzyl-1,2,3,6-tetrahydropyridin-4-yl)-5-ethoxy-1H-indole (D2AAK1_3) as Dopamine D₂ Receptor Ligand
Molecules (Basel, Switzerland), Vol. 23, Núm. 9
2016
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Erratum: Corrigendum to “In vitro, molecular modeling and behavioral studies of ‘3-{[4-(5-methoxy-1H-indol-3-yl)-1,2,3,6-tetrahydropyridin-1-yl]methyl}-1,2-dihydroquinolin-2-one (D2AAK1) as a potential antipsychotic” (Neurochemistry International (2016) 96 (84–99)(10.1016/j.neuint.2016.03.003)(S0197018616300304))
Neurochemistry International
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In vitro, molecular modeling and behavioral studies of 3-{[4-(5-methoxy-1H-indol-3-yl)-1,2,3,6-tetrahydropyridin-1-yl]methyl}-1,2-dihydroquinolin-2-one (D2AAK1) as a potential antipsychotic
Neurochemistry International, Vol. 96, pp. 84-99
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Structure-Based Virtual Screening for Dopamine D2 Receptor Ligands as Potential Antipsychotics
ChemMedChem, Vol. 11, Núm. 7, pp. 718-729
2014
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Application of BRET for studying G protein-coupled receptors
Mini-Reviews in Medicinal Chemistry, Vol. 14, Núm. 5, pp. 411-425