Publicacións en colaboración con investigadores/as de Instituto de Química Médica (6)

2017

  1. Targeting PDE10A GAF domain with small molecules: A way for allosteric modulation with anti-inflammatory effects

    Molecules, Vol. 22, Núm. 9

2014

  1. Modulation of cAMP-specific PDE without emetogenic activity: New sulfide-like PDE7 inhibitors

    Journal of Medicinal Chemistry, Vol. 57, Núm. 20, pp. 8590-8607

2013

  1. Unraveling phosphodiesterase surfaces. Identification of phosphodiesterase 7 allosteric modulation cavities

    European Journal of Medicinal Chemistry, Vol. 70, pp. 781-788

2012

  1. Effect of phosphodiesterase 7 (PDE7) inhibitors in experimental autoimmune encephalomyelitis mice. Discovery of a new chemically diverse family of compounds

    Journal of Medicinal Chemistry, Vol. 55, Núm. 7, pp. 3274-3284

  2. Identification in Silico and experimental validation of novel phosphodiesterase 7 inhibitors with efficacy in experimental autoimmune encephalomyelitis mice

    ACS Chemical Neuroscience, Vol. 3, Núm. 10, pp. 793-803

  3. Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model

    European Journal of Medicinal Chemistry, Vol. 47, Núm. 1, pp. 175-185