Publikationen in Zusammenarbeit mit Forschern von Universidade Do Porto (12)

2023

  1. 8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies

    European Journal of Medicinal Chemistry, Vol. 248

  2. Stapling Amantadine to Melanostatin Neuropeptide: Discovery of Potent Positive Allosteric Modulators of the D2 Receptors

    ACS Medicinal Chemistry Letters, Vol. 14, Núm. 12, pp. 1656-1663

2021

  1. Discovery of New Potent Positive Allosteric Modulators of Dopamine D2Receptors: Insights into the Bioisosteric Replacement of Proline to 3-Furoic Acid in the Melanostatin Neuropeptide

    Journal of Medicinal Chemistry, Vol. 64, Núm. 9, pp. 6209-6220

  2. Synthesis, Pharmacological, and Biological Evaluation of 2-Furoyl-Based MIF-1 Peptidomimetics and the Development of a General-Purpose Model for Allosteric Modulators (ALLOPTML)

    ACS Chemical Neuroscience, Vol. 12, Núm. 1, pp. 203-215

2019

  1. Synthesis, Pharmacological, and Biological Evaluation of MIF-1 Picolinoyl Peptidomimetics as Positive Allosteric Modulators of D2R

    ACS Chemical Neuroscience, Vol. 10, Núm. 8, pp. 3690-3702

2017

  1. Cis-Platinum Complex Encapsulated in Self-Assembling Cyclic Peptide Dimers

    Organic Letters, Vol. 19, Núm. 10, pp. 2560-2563

2013

  1. Synthesis and allosteric modulation of the dopamine receptor by peptide analogs of l-prolyl-l-leucyl-glycinamide (PLG) modified in the l-proline or l-proline and l-leucine scaffolds

    European Journal of Medicinal Chemistry, Vol. 69, pp. 146-158

2010

  1. Synthesis and pharmacological evaluation of novel 1,3,8- and 1,3,7,8-substituted xanthines as adenosine receptor antagonists

    Bioorganic and Medicinal Chemistry, Vol. 18, Núm. 5, pp. 2001-2009

  2. Synthesis and pharmacological evaluation of novel substituted 9-deazaxanthines as A2B receptor antagonists

    European Journal of Medicinal Chemistry, Vol. 45, Núm. 7, pp. 2884-2892

  3. Synthesis of theophylline derivatives and study of their activity as antagonists at adenosine receptors

    Bioorganic and Medicinal Chemistry, Vol. 18, Núm. 6, pp. 2081-2088

2009

  1. Synthesis and pharmacological evaluation of novel 1- and 8-substituted-3-furfuryl xanthines as adenosine receptor antagonists

    Bioorganic and Medicinal Chemistry, Vol. 17, Núm. 18, pp. 6755-6760

  2. Synthesis of novel 1-alkyl-8-substituted-3-(3-methoxypropyl) xanthines as putative A2B receptor antagonists

    Bioorganic and Medicinal Chemistry, Vol. 17, Núm. 9, pp. 3426-3432