José Manuel
Brea Floriani
Senior university lecturer
Abel
Crespo Gavilán
Publications by the researcher in collaboration with Abel Crespo Gavilán (5)
2022
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Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A1Antagonists
Journal of Medicinal Chemistry, Vol. 65, Núm. 3, pp. 2091-2106
2021
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3,4-Dihydropyrimidin-2(1H)-ones as Antagonists of the Human A2B Adenosine Receptor: Optimization, Structure-Activity Relationship Studies, and Enantiospecific Recognition
Journal of medicinal chemistry, Vol. 64, Núm. 1, pp. 458-480
2017
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3-Oxopyridazin-5-yl-Chalcone Hybrids: Potent Antiplatelet Agents That Prevent Glycoprotein IIb/IIIa Activation
ChemistrySelect, Vol. 2, Núm. 17, pp. 4920-4933
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Exploring the influence of the substituent at position 4 in a series of 3,4-dihydropyrimidin-2(1H)-one A2B adenosine receptor antagonists
Chemistry of Heterocyclic Compounds, Vol. 53, Núm. 3, pp. 316-322
2013
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Discovery of 3,4-dihydropyrimidin-2(1 H)-ones as a novel class of potent and selective A2B adenosine receptor antagonists
ACS Medicinal Chemistry Letters, Vol. 4, Núm. 11, pp. 1031-1036