José Manuel
Brea Floriani
Profesor titular de universidade
![Foto de Alba](/img/nophoto.png)
Alba
Iglesias Fernández
Publicacións nas que colabora con Alba Iglesias Fernández (8)
2021
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His452Tyr polymorphism in the human 5-HT2A receptor affects clozapine-induced signaling networks revealed by quantitative phosphoproteomics
Biochemical Pharmacology, Vol. 185
2020
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Essential role of the C148–C227 disulphide bridge in the human 5-HT2A homodimeric receptor
Biochemical Pharmacology, Vol. 177
2017
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Development of Fluorescent Probes that Target Serotonin 5-HT2B Receptors
Scientific Reports, Vol. 7, Núm. 1
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Serotonin 2A receptor disulfide bridge integrity is crucial for ligand binding to different signalling states but not for its homodimerization
European Journal of Pharmacology, Vol. 815, pp. 138-146
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Serotonin-2A homodimers are needed for signalling via both phospholipase A2 and phospholipase C in transfected CHO cells
European Journal of Pharmacology, Vol. 800, pp. 63-69
2016
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Development of a Multiplex Assay for Studying Functional Selectivity of Human Serotonin 5-HT2A Receptors and Identification of Active Compounds by High-Throughput Screening
Journal of Biomolecular Screening, Vol. 21, Núm. 8, pp. 816-823
2015
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Detection of new biased agonists for the serotonin 5-ht2a receptor: modeling and experimental validation
Molecular Pharmacology, Vol. 87, Núm. 4, pp. 740-746
2013
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Synthesis and binding affinity of new 1,4-disubstituted triazoles as potential dopamine D3 receptor ligands
Bioorganic and Medicinal Chemistry Letters, Vol. 23, Núm. 20, pp. 5586-5591