José Manuel
Brea Floriani
Profesor titular de universidade
![Foto de Mercè](/img/nophoto.png)
Mercè
Pallàs Lliberia
Publicacións nas que colabora con Mercè Pallàs Lliberia (12)
2022
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Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 236
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Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease
Journal of Medicinal Chemistry, Vol. 65, Núm. 6, pp. 4909-4925
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Insights into the Pharmacokinetics and In Vitro Cell‐Based Studies of the Imidazoline I2 Receptor Ligand B06
International Journal of Molecular Sciences, Vol. 23, Núm. 10
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Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors
Journal of medicinal chemistry, Vol. 65, Núm. 20, pp. 13660-13680
2021
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Benzofuranyl-2-imidazoles as imidazoline I2 receptor ligands for Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 222
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From the Design to the in Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis
Journal of Medicinal Chemistry, Vol. 64, Núm. 9, pp. 5429-5446
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From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects
European Journal of Medicinal Chemistry, Vol. 225
2020
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A novel NMDA receptor antagonist protects against cognitive decline presented by senescent mice
Pharmaceutics, Vol. 12, Núm. 3
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Bicyclic α-Iminophosphonates as High Affinity Imidazoline I2 Receptor Ligands for Alzheimer's Disease
Journal of Medicinal Chemistry, Vol. 63, Núm. 7, pp. 3610-3633
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Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6
Journal of Medicinal Chemistry, Vol. 63, Núm. 17, pp. 9360-9390
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Erratum: Bicyclic α-Iminophosphonates as High Affinity Imidazoline I2Receptor Ligands for Alzheimer's Disease (Journal of Medicinal Chemistry (2020) 63:7 (3610−3633) DOI: 10.1021/acs.jmedchem.9b02080)
Journal of Medicinal Chemistry
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Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer’s Disease
Neurotherapeutics, Vol. 17, Núm. 4, pp. 1825-1835