José Manuel
Brea Floriani
Profesor titular de universidade
![Foto de Enrique](/img/nophoto.png)
Enrique
Raviña Rubira
Publicacións nas que colabora con Enrique Raviña Rubira (17)
2017
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3-Oxopyridazin-5-yl-Chalcone Hybrids: Potent Antiplatelet Agents That Prevent Glycoprotein IIb/IIIa Activation
ChemistrySelect, Vol. 2, Núm. 17, pp. 4920-4933
2014
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Synthesis and biological evaluation of a series of aminoalkyl-tetralones and tetralols as dual dopamine/serotonin ligands
European Journal of Medicinal Chemistry, Vol. 71, pp. 237-249
2011
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Potential atypical antipsychotics: Synthesis, binding affinity and SAR of new heterocyclic bioisosteric butyrophenone analogues as multitarget ligands
MedChemComm, Vol. 2, Núm. 12, pp. 1194-1200
2009
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Synthesis and binding affinity of potential atypical antipsychotics with the tetrahydroquinazolinone motif
Bioorganic and Medicinal Chemistry Letters, Vol. 19, Núm. 21, pp. 6059-6062
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Synthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D3 receptor ligands
Bioorganic and Medicinal Chemistry Letters, Vol. 19, Núm. 6, pp. 1773-1778
2008
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1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor
Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 6, pp. 2852-2869
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Corrigendum to "1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor" [Bioorg. Med. Chem. 16 (2008) 2852-2869] (DOI:10.1016/j.bmc.2008.01.002)
Bioorganic and Medicinal Chemistry
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Synthesis, adenosine receptor binding and 3D-QSAR of 4-substituted 2-(2′-furyl)-1,2,4-triazolo[1,5-a]quinoxalines
Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 4, pp. 2103-2113
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Synthesis, binding affinity, and molecular docking analysis of new benzofuranone derivatives as potential antipsychotics
Journal of Medicinal Chemistry, Vol. 51, Núm. 19, pp. 6085-6094
2007
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Multistructure 3D-QSAR studies on a series of conformationally constrained butyrophenones docked into a new homology model of the 5-HT2A receptor
Journal of Medicinal Chemistry, Vol. 50, Núm. 14, pp. 3242-3255
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Synthesis and binding affinity of new pyrazole and isoxazole derivatives as potential atypical antipsychotics
Bioorganic and Medicinal Chemistry Letters, Vol. 17, Núm. 17, pp. 4873-4877
2006
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QF2004B, a potential antipsychotic butyrophenone derivative with similar pharmacological properties to clozapine
Neuropharmacology, Vol. 51, Núm. 2, pp. 251-262
2005
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Synthesis and binding affinity of novel 3-aminoethyl-1-tetralones, potential atypical antipsychotics
Bioorganic and Medicinal Chemistry Letters, Vol. 15, Núm. 12, pp. 3063-3066
2004
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Chemoenzymatic synthesis and binding affinity of novel (R)- and (S)-3-aminomethyl-1-tetralones, potential atypical antipsychotics
Bioorganic and Medicinal Chemistry Letters, Vol. 14, Núm. 3, pp. 585-589
2003
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Conformationally constrained butyrophenones as new pharmacological tools to study 5-HT2A and 5-HT2C receptor behaviours
European Journal of Medicinal Chemistry
2002
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New serotonin 5-HT2A, 5-HT2B, and 5-HT2C receptor antagonists: Synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo and heterocycloalkanones
Journal of Medicinal Chemistry, Vol. 45, Núm. 1, pp. 54-71
2000
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Butyrophenone analogues in the carbazole series as potential atypical antipsychotics: Synthesis and determination of affinities at D2, 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors
European Journal of Medicinal Chemistry, Vol. 35, Núm. 1, pp. 83-95