Publicacións (399) Publicacións nas que participase algún/ha investigador/a

2024

  1. 2-Aryladenine Derivatives as a Potent Scaffold for Adenosine Receptor Antagonists: The 6-Morpholino Derivatives

    Molecules, Vol. 29, Núm. 11

  2. Altered dynamics of calcium fluxes and mitochondrial metabolism in platelet activation-related disease and aging

    Life Sciences, Vol. 351

  3. Design, synthesis and validation of a new Crimped Head-Piece for DNA-Encoded libraries generation

    Bioorganic and Medicinal Chemistry, Vol. 99

  4. Design, synthesis, and biological evaluation of tetrahydropyrimidine analogue as GSK-3β/Aβ aggregation inhibitor and anti-Alzheimer's agent

    Bioorganic Chemistry, Vol. 153

  5. Discovery and in vitro Evaluation of Novel Serotonin 5-HT2A Receptor Ligands Identified Through Virtual Screening

    ChemMedChem, Vol. 19, Núm. 14

  6. Effect of Bulky N-Dibenzofuranylmethyl Substitution on the 5-HT2 Receptor Affinity and Efficacy of a Psychedelic Phenethylamine

    ACS Chemical Neuroscience, Vol. 15, Núm. 3, pp. 608-616

  7. Exploring Biginelli-based scaffolds as A2B adenosine receptor antagonists: Unveiling novel structure-activity relationship trends, lead compounds, and potent colorectal anticancer agents

    Biomedicine and Pharmacotherapy, Vol. 173

  8. Fármacos analgésicos opiáceos

    Castells Hernández farmacología en enfermería (Elsevier), pp. 124-134

  9. G protein-specific mechanisms in the serotonin 5-HT2A receptor regulate psychosis-related effects and memory deficits

    Nature communications, Vol. 15, Núm. 1, pp. 4307

  10. High-Throughput DNA-Encoded Libraries Affinity Selection Platform for Binder Identification with Solid Support Protein Immobilization

    Assay and Drug Development Technologies, Vol. 22, Núm. 4, pp. 192-202

  11. High-throughput nephelometry methodology for qualitative determination of aqueous solubility of chemical libraries

    SLAS Discovery, Vol. 29, Núm. 3

  12. In vitro models for neuropathic pain phenotypic screening in brain therapeutics

    Pharmacological Research, Vol. 202

  13. N-Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as Fluorescent Probes to Detect Microglia Activation through the Imaging of Cannabinoid Receptor Subtype 2 (CB2R)

    Journal of Medicinal Chemistry, Vol. 67, Núm. 13, pp. 11003-11023

  14. Nanoemulsions and nanocapsules as carriers for the development of intranasal mRNA vaccines

    Drug Delivery and Translational Research, Vol. 14, Núm. 8, pp. 2046-2061

  15. Stepwise Structural Simplification of the Dihydroxyanthraquinone Moiety of a Multitarget Rhein-Based Anti-Alzheimer Lead to Improve Drug Metabolism and Pharmacokinetic Properties

    Pharmaceutics, Vol. 16, Núm. 8

  16. Ultra-high throughput-based screening for the discovery of antiplatelet drugs affecting receptor dependent calcium signaling dynamics

    Scientific Reports, Vol. 14, Núm. 1

2023

  1. 8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies

    European Journal of Medicinal Chemistry, Vol. 248

  2. A Robust and Efficient FRET-Based Assay for Cannabinoid Receptor Ligands Discovery

    Molecules, Vol. 28, Núm. 24

  3. A continuous in silico learning strategy to identify safety liabilities in compounds used in the leather and textile industry

    Archives of Toxicology, Vol. 97, Núm. 4, pp. 1091-1111

  4. Design and biopharmaceutical preclinical characterisation of a new thermosensitive hydrogel for the removal of gastric polyps

    International Journal of Pharmaceutics, Vol. 635, pp. 122706