Bioloxía de membranas e mecanismos de transducción de sinais en farmacoloxía aplicada.
BioFarma
Universitat Autònoma de Barcelona
Barcelona, EspañaPublicacións en colaboración con investigadores/as de Universitat Autònoma de Barcelona (42)
2024
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Design, synthesis, and biological evaluation of tetrahydropyrimidine analogue as GSK-3β/Aβ aggregation inhibitor and anti-Alzheimer's agent
Bioorganic Chemistry, Vol. 153
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Stepwise Structural Simplification of the Dihydroxyanthraquinone Moiety of a Multitarget Rhein-Based Anti-Alzheimer Lead to Improve Drug Metabolism and Pharmacokinetic Properties
Pharmaceutics, Vol. 16, Núm. 8
2022
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Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 236
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Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease
Journal of Medicinal Chemistry, Vol. 65, Núm. 6, pp. 4909-4925
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Genomic Validation of Endometrial Cancer Patient-Derived Xenograft Models as a Preclinical Tool
International Journal of Molecular Sciences, Vol. 23, Núm. 11
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Insights into the Pharmacokinetics and In Vitro Cell‐Based Studies of the Imidazoline I2 Receptor Ligand B06
International Journal of Molecular Sciences, Vol. 23, Núm. 10
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Structure-Based Virtual Screening and in vitro and in vivo Analyses Revealed Potent Methyltransferase G9a Inhibitors as Prospective Anti-Alzheimer's Agents
ChemMedChem, Vol. 17, Núm. 13
2021
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Benzofuranyl-2-imidazoles as imidazoline I2 receptor ligands for Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 222
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From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects
European Journal of Medicinal Chemistry, Vol. 225
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Modeling ANXA2-overexpressing circulating tumor cells homing and high throughput screening for metastasis impairment in endometrial carcinomas
Biomedicine and Pharmacotherapy, Vol. 140
2020
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Bicyclic α-Iminophosphonates as High Affinity Imidazoline I2 Receptor Ligands for Alzheimer's Disease
Journal of Medicinal Chemistry, Vol. 63, Núm. 7, pp. 3610-3633
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Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6
Journal of Medicinal Chemistry, Vol. 63, Núm. 17, pp. 9360-9390
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Intraoperative Human Papillomavirus Test Predicts 24-Month High-Grade Squamous Intraepithelial Lesion Recurrence Saving Costs: A Prospective Cohort Study
Journal of Lower Genital Tract Disease, Vol. 24, Núm. 4, pp. 367-371
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Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer’s Disease
Neurotherapeutics, Vol. 17, Núm. 4, pp. 1825-1835
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Pharmacology and preclinical validation of a novel anticancer compound targeting PEPCK-M
Biomedicine and Pharmacotherapy, Vol. 121
2019
2018
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Added Value of Estrogen Receptor, Progesterone Receptor, and L1 Cell Adhesion Molecule Expression to Histology-Based Endometrial Carcinoma Recurrence Prediction Models: An ENITEC Collaboration Study
International Journal of Gynecological Cancer, Vol. 28, Núm. 3, pp. 514-523
2017
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Metabolomic and Lipidomic Profiling Identifies the Role of the RNA Editing Pathway in Endometrial Carcinogenesis
Scientific Reports, Vol. 7, Núm. 1
2016
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Exosome-like vesicles in uterine aspirates: A comparison of ultracentrifugation-based isolation protocols
Journal of Translational Medicine, Vol. 14, Núm. 1
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L1CAM expression in endometrial carcinomas: An ENITEC collaboration study
British Journal of Cancer, Vol. 115, Núm. 6, pp. 716-724