Eduardo
Dominguez Medina
Publicacións nas que colabora con Eduardo Dominguez Medina (23)
2024
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Design, synthesis and validation of a new Crimped Head-Piece for DNA-Encoded libraries generation
Bioorganic and Medicinal Chemistry, Vol. 99
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High-Throughput DNA-Encoded Libraries Affinity Selection Platform for Binder Identification with Solid Support Protein Immobilization
Assay and Drug Development Technologies, Vol. 22, Núm. 4, pp. 192-202
2022
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Identification of Sodium Transients Through NaV1.5 Channels as Regulators of Differentiation in Immortalized Dorsal Root Ganglia Neurons
Frontiers in Cellular Neuroscience, Vol. 16
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Katacine Is a New Ligand of CLEC-2 that Acts as a Platelet Agonist
Thrombosis and Haemostasis, Vol. 122, Núm. 8, pp. 1361-1368
2021
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Identification of Novel Regulators of Zalcitabine-Induced Neuropathic Pain
ACS Chemical Neuroscience, Vol. 12, Núm. 14, pp. 2619-2628
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Normalization of DNA encoded library affinity selection results driven by high throughput sequencing and HPLC purification
Bioorganic and Medicinal Chemistry, Vol. 40
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The pi3kδ inhibitor idelalisib diminishes platelet function and shows antithrombotic potential
International Journal of Molecular Sciences, Vol. 22, Núm. 7
2020
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A Comprehensive Tyrosine Phosphoproteomic Analysis Reveals Novel Components of the Platelet CLEC-2 Signaling Cascade
Thrombosis and Haemostasis, Vol. 120, Núm. 2, pp. 262-276
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Author Correction: Identification and characterization of Cardiac Glycosides as senolytic compounds (Nature Communications, (2019), 10, 1, (4731), 10.1038/s41467-019-12888-x)
Nature Communications
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Discovery of novel immunopharmacological ligands targeting the IL-17 inflammatory pathway
International Immunopharmacology, Vol. 89
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Flux-based assay for the identification of autophagy modulators for osteoarthritis
Journal of Visualized Experiments, Vol. 2020, Núm. 161, pp. 1-14
2019
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Fibrates as drugs with senolytic and autophagic activity for osteoarthritis therapy
EBioMedicine, Vol. 45, pp. 588-605
2018
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tagFinder: A Novel Tag Analysis Methodology That Enables Detection of Molecules from DNA-Encoded Chemical Libraries
SLAS Discovery, Vol. 23, Núm. 5, pp. 397-404
2017
2010
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Emerging opportunities and concerns for drug discovery at serotonin 5-5-HT2B receptors
Current Topics in Medicinal Chemistry, Vol. 10, Núm. 5, pp. 493-503
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In silico directed chemical probing of the adenosine receptor family
Bioorganic and Medicinal Chemistry, Vol. 18, Núm. 9, pp. 3043-3052
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Synthesis, 3D-QSAR, and structural modeling of benzolactam derivatives with binding affinity for the D2and D3 receptors
ChemMedChem, Vol. 5, Núm. 8, pp. 1300-1317
2009
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Synthesis and binding affinity of potential atypical antipsychotics with the tetrahydroquinazolinone motif
Bioorganic and Medicinal Chemistry Letters, Vol. 19, Núm. 21, pp. 6059-6062
2008
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A new chemical tool (C0036E08) supports the role of adenosine A2B receptors in mediating human mast cell activation
Biochemical Pharmacology, Vol. 76, Núm. 7, pp. 912-921
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Synthesis, binding affinity, and molecular docking analysis of new benzofuranone derivatives as potential antipsychotics
Journal of Medicinal Chemistry, Vol. 51, Núm. 19, pp. 6085-6094