Publications in collaboration with researchers from KU Leuven (14)

2007

  1. ANN-QSAR model for selection of anticancer leads from structurally heterogeneous series of compounds

    European Journal of Medicinal Chemistry, Vol. 42, Núm. 5, pp. 580-585

2006

  1. Stochastic entropy QSAR for the in silico discovery of anticancer compounds: Prediction, synthesis, and in vitro assay of new purine carbanucleosides

    Bioorganic and Medicinal Chemistry, Vol. 14, Núm. 4, pp. 1095-1107

  2. Synthesis and anti-HIV activity of novel cyclopentenyl nucleoside analogues of 8-azapurine

    Chemical and Pharmaceutical Bulletin, Vol. 54, Núm. 10, pp. 1418-1420

2005

  1. Pyridazine derivatives. Part 40: Reactivity of 5-alkynylpyridazin-3(2H)- ones toward hydrochloric acid

    Tetrahedron, Vol. 61, Núm. 20, pp. 4785-4791

  2. QSAR for anti-RNA-virus activity, synthesis, and assay of anti-RSV carbonucleosides given a unified representation of spectral moments, quadratic, and topologic indices

    Bioorganic and Medicinal Chemistry Letters, Vol. 15, Núm. 6, pp. 1651-1657

2004

  1. Pyridazine derivatives. Part 38: Efficient Heck alkenylation at position 5 of the 6-phenyl-3(2H)-pyridazinone system

    Tetrahedron Letters, Vol. 45, Núm. 17, pp. 3459-3463

  2. Pyridazine derivatives. Part 39: Reactivity of 5-iodopyridazin-3(2H)-ones in palladium-catalysed reactions

    Tetrahedron, Vol. 60, Núm. 52, pp. 12177-12189

2003

  1. Purine derivatives of 1,2-disubstituted cyclohexane analogues of nucleosides

    Nucleosides, Nucleotides and Nucleic Acids

2002

  1. Synthesis, conformational analysis and antiviral and antitumoral activity of new 1,2-disubstituted carbocyclic nucleosides

    European Journal of Medicinal Chemistry, Vol. 37, Núm. 9, pp. 755-760

2000

  1. A novel approach for the virtual screening and rational design of anticancer compounds

    Journal of Medicinal Chemistry, Vol. 43, Núm. 10, pp. 1975-1985

  2. Design, synthesis, conformational analysis and biological activities of purine-based 1,2-di-substituted carbocyclic nucleosides

    Chemical and Pharmaceutical Bulletin, Vol. 48, Núm. 2, pp. 293-295

1999

  1. Synthesis and biological evaluation of 1,2-disubstituted carbonucleosides of 6-substituted purine and 8-azapurine

    Nucleosides and Nucleotides

1997

  1. Synthesis and biological activity of some 2-aminopurine carbonucleosides

    Nucleosides and Nucleotides

1995

  1. Synthesis and antiviral activity of 1,2-carbonucleosides

    Nucleosides and Nucleotides, Vol. 14, Núm. 3-5, pp. 521-523