Publikationen in Zusammenarbeit mit Forschern von University of Cambridge (16)

2022

  1. Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry

    Journal of the American Chemical Society, Vol. 144, Núm. 12, pp. 5284-5294

2020

  1. Sequential dual site-selective protein labelling enabled by lysine modification

    Bioorganic and Medicinal Chemistry, Vol. 28, Núm. 22

2019

  1. Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents

    Nature Protocols, Vol. 14, Núm. 1, pp. 86-99

  2. Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification

    ACS Central Science, Vol. 5, Núm. 8, pp. 1417-1424

  3. Lysine Bioconjugation on Native Albumin with a Sulfonyl Acrylate Reagent

    Methods in Molecular Biology (Humana Press Inc.), pp. 25-37

  4. Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine-Selective Protein Modification and Charge Modulation

    Angewandte Chemie - International Edition, Vol. 58, Núm. 20, pp. 6640-6644

2018

  1. A silicon-labelled amino acid suitable for late-stage fluorination and unexpected oxidative cleavage reactions in the preparation of a key intermediate in the Strecker synthesis

    Peptide Science, Vol. 110, Núm. 3

  2. A thioether-directed palladium-cleavable linker for targeted bioorthogonal drug decaging

    Chemical Science, Vol. 9, Núm. 17, pp. 4185-4189

  3. Chemo- and Regioselective Lysine Modification on Native Proteins

    Journal of the American Chemical Society, Vol. 140, Núm. 11, pp. 4004-4017

  4. Learning from nature: The role of albumin in drug delivery

    Future Medicinal Chemistry

  5. Synthesis and Biological Evaluation of Homogeneous Thiol-Linked NHC*-Au-Albumin and -Trastuzumab Bioconjugates

    Chemistry - A European Journal, Vol. 24, Núm. 47, pp. 12250-12253

  6. Trends in patented chromones for skin diseases

    Pharmaceutical patent analyst, Vol. 7, Núm. 3, pp. 107-109

2017

  1. Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation

    Journal of the American Chemical Society, Vol. 139, Núm. 50, pp. 18365-18375

  2. Trends in therapeutic drug conjugates for bacterial diseases: a patent review

    Expert Opinion on Therapeutic Patents, Vol. 27, Núm. 2, pp. 179-189

2016

  1. Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents

    Nature Communications, Vol. 7

2004

  1. Mitomycin dimers: Polyfunctional cross-linkers of DNA

    Journal of Medicinal Chemistry, Vol. 47, Núm. 12, pp. 3308-3319