I+D de fármacos
GI-1606
Universidad Autónoma de Chile
Temuco, ChilePublikationen in Zusammenarbeit mit Forschern von Universidad Autónoma de Chile (52)
2023
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8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies
European Journal of Medicinal Chemistry, Vol. 248
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Design of 3-Phenylcoumarins and 3-Thienylcoumarins as Potent Xanthine Oxidase Inhibitors: Synthesis, Biological Evaluation, and Docking Studies
ChemMedChem, Vol. 18, Núm. 21
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Modulating Cytotoxicity with Lego-like Chemistry: Upgrading Mitochondriotropic Antioxidants with Prototypical Cationic Carrier Bricks
Journal of Medicinal Chemistry, Vol. 66, Núm. 3, pp. 1835-1851
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Phytochemical Analysis and Antiproliferative Activity of Ulex gallii Planch. (Fabaceae), a Medicinal Plant from Galicia (Spain)
Molecules, Vol. 28, Núm. 1
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Propargylamine: an important moiety in drug discovery
Future Medicinal Chemistry, Vol. 15, Núm. 1, pp. 211-224
2022
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Coumarin-Resveratrol-Inspired Hybrids as Monoamine Oxidase B Inhibitors: 3-Phenylcoumarin versus trans-6-Styrylcoumarin
Molecules, Vol. 27, Núm. 3
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Design and synthesis of chromone-based monoamine oxidase B inhibitors with improved drug-like properties
European Journal of Medicinal Chemistry, Vol. 239
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Hydroxy-3-Phenylcoumarins as Multitarget Compounds for Skin Aging Diseases: Synthesis, Molecular Docking and Tyrosinase, Elastase, Collagenase and Hyaluronidase Inhibition, and Sun Protection Factor
Molecules, Vol. 27, Núm. 20
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Synthesis and Vasorelaxant Activity of Nitrate−Coumarin Derivatives
ChemMedChem, Vol. 17, Núm. 21
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Thiocoumarins: From the Synthesis to the Biological Applications
Molecules, Vol. 27, Núm. 15
2021
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3-phenylcoumarins as a privileged scaffold in medicinal chemistry: The landmarks of the past decade
Molecules, Vol. 26, Núm. 21
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4-Oxoquinolines and monoamine oxidase: When tautomerism matters
European Journal of Medicinal Chemistry, Vol. 213
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7-Amidocoumarins as Multitarget Agents against Neurodegenerative Diseases: Substitution Pattern Modulation
ChemMedChem, Vol. 16, Núm. 1, pp. 179-186
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Combined 3D-QSAR and docking analysis for the design and synthesis of chalcones as potent and selective monoamine oxidase B inhibitors
Bioorganic Chemistry, Vol. 108
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Curcumin–coumarin hybrid analogues as multitarget agents in neurodegenerative disorders
Molecules, Vol. 26, Núm. 15
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Study of a Selected Series of 3- and 4-Arylcoumarins as Antifungal Agents against Dermatophytic Fungi: T. rubrum and T. mentagrophytes
ChemistrySelect, Vol. 6, Núm. 37, pp. 9981-9989
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Trending Topics on Coumarin and Its Derivatives in 2020
Molecules (Basel, Switzerland), Vol. 26, Núm. 2
2020
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3-Arylcoumarins as highly potent and selective monoamine oxidase B inhibitors: Which chemical features matter?
Bioorganic Chemistry, Vol. 101
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Adenosine receptor ligands: Coumarin–Chalcone hybrids as modulating agents on the activity of hARs
Molecules, Vol. 25, Núm. 18
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Coumarin-Rasagiline Hybrids as Potent and Selective hMAO-B Inhibitors, Antioxidants, and Neuroprotective Agents
ChemMedChem, Vol. 15, Núm. 6, pp. 532-538