I+D de fármacos
GI-1606
Universidad de Chile
Santiago de Chile, ChilePublikationen in Zusammenarbeit mit Forschern von Universidad de Chile (20)
2022
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Synthesis and study of the trypanocidal activity of catechol-containing 3-arylcoumarins, inclusion in β-cyclodextrin complexes and combination with benznidazole
Arabian Journal of Chemistry, Vol. 15, Núm. 3
2021
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Chemical and biological analysis of 4-acyloxy-3-nitrocoumarins as trypanocidal agents
Arabian Journal of Chemistry, Vol. 14, Núm. 3
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New benzimidazolequinones as trypanosomicidal agents
Bioorganic Chemistry, Vol. 111
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Theobroma cacao L. compounds: Theoretical study and molecular modeling as inhibitors of main SARS-CoV-2 protease
Biomedicine and Pharmacotherapy, Vol. 140
2020
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In Silico Study of Coumarins and Quinolines Derivatives as Potent Inhibitors of SARS-CoV-2 Main Protease
Frontiers in Chemistry, Vol. 8
2018
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Evaluation of trypanocidal and antioxidant activities of a selected series of 3-amidocoumarins
Medicinal Chemistry, Vol. 14, Núm. 6, pp. 573-584
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Targeting α -(1,4)-glucosidase in diabetes mellitus type 2: The role of new synthetic coumarins as potent inhibitors
Current Topics in Medicinal Chemistry, Vol. 18, Núm. 27, pp. 2327-2337
2017
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A medical approach to the monoamine oxidase inhibition by using 7H-benzo[e]perimidin-7-one derivatives
Current Topics in Medicinal Chemistry, Vol. 17, Núm. 7
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Synthesis, antioxidant and antichagasic properties of a selected series of hydroxy-3-arylcoumarins
Bioorganic and Medicinal Chemistry, Vol. 25, Núm. 2, pp. 621-632
2016
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Evaluation of Antioxidant and Antitrypanosomal Properties of a Selected Series of Synthetic 3-Carboxamidocoumarins
ChemistrySelect, Vol. 1, Núm. 15, pp. 4957-4964
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Facing chagas' disease: Trypanocidal properties of new coumarinchalcone scaffolds
Medicinal Chemistry, Vol. 12, Núm. 6, pp. 537-543
2015
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Anxiolytic-like effects of 7H-benzo[e]perimidin-7-one derivatives through elevated plus-maze test in mice
Current Topics in Medicinal Chemistry, Vol. 15, Núm. 17, pp. 1750-1754
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Interest of antioxidant agents in parasitic diseases. The case study of coumarins
Current Topics in Medicinal Chemistry, Vol. 15, Núm. 9, pp. 850-856
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Study of coumarin-resveratrol hybrids as potent antioxidant compounds
Molecules, Vol. 20, Núm. 2, pp. 3290-3308
2013
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Host-guest interaction between new nitrooxoisoaporphine and β-cyclodextrins: Synthesis, electrochemical, electron spin resonance and molecular modeling studies
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, Vol. 102, pp. 226-234
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Remarkable antioxidant properties of a series of hydroxy-3-arylcoumarins
Bioorganic and Medicinal Chemistry, Vol. 21, Núm. 13, pp. 3900-3906
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Synthesis and electrochemical and biological studies of novel coumarin-chalcone hybrid compounds
Journal of Medicinal Chemistry, Vol. 56, Núm. 15, pp. 6136-6145
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Synthesis and evaluation of antioxidant and trypanocidal properties of a selected series of coumarin derivatives
Future Medicinal Chemistry, Vol. 5, Núm. 16, pp. 1911-1922
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Synthesis of coumarin-chalcone hybrids and evaluation of their antioxidant and trypanocidal properties
MedChemComm, Vol. 4, Núm. 6, pp. 993-1000
2012
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Antitrypanosomal and antioxidant properties of 4-hydroxycoumarins derivatives
Bioorganic and Medicinal Chemistry Letters, Vol. 22, Núm. 17, pp. 5569-5573