I+D de fármacos
GI-1606
University of Würzburg
Wurzburgo, AlemaniaPublikationen in Zusammenarbeit mit Forschern von University of Würzburg (10)
2020
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Adenosine receptor ligands: Coumarin–Chalcone hybrids as modulating agents on the activity of hARs
Molecules, Vol. 25, Núm. 18
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Structure-Based Optimization of Coumarin hA3 Adenosine Receptor Antagonists
Journal of Medicinal Chemistry, Vol. 63, Núm. 5, pp. 2577-2587
2018
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Coumarins and adenosine receptors: New perceptions in structure–affinity relationships
Chemical Biology and Drug Design, Vol. 91, Núm. 1, pp. 245-256
2016
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Progress in the development of small molecules as new human A3 adenosine receptor ligands based on the 3-thiophenylcoumarin core
MedChemComm, Vol. 7, Núm. 5, pp. 845-852
2015
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Development of novel adenosine receptor ligands based on the 3-amidocoumarin scaffold
Bioorganic Chemistry, Vol. 61, pp. 1-6
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Navigating in chromone chemical space: Discovery of novel and distinct A3 adenosine receptor ligands
RSC Advances, Vol. 5, Núm. 96, pp. 78572-78585
2013
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Chalcone-based derivatives as new scaffolds for hA3 adenosine receptor antagonists
Journal of Pharmacy and Pharmacology, Vol. 65, Núm. 5, pp. 697-703
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Synthesis and adenosine receptors binding affinities of a series of 3-arylcoumarins
Journal of Pharmacy and Pharmacology, Vol. 65, Núm. 11, pp. 1590-1597
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Targeting adenosine receptors with coumarins: Synthesis and binding activities of amide and carbamate derivatives
Journal of Pharmacy and Pharmacology, Vol. 65, Núm. 1, pp. 30-34
2012
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Discovery of novel A 3 adenosine receptor ligands based on chromone scaffold
Biochemical Pharmacology, Vol. 84, Núm. 1, pp. 21-29