Publications by the researcher in collaboration with XERARDO XUSTO GARCIA MERA (17)

2021

  1. 3,4-Dihydropyrimidin-2(1H)-ones as Antagonists of the Human A2B Adenosine Receptor: Optimization, Structure-Activity Relationship Studies, and Enantiospecific Recognition

    Journal of medicinal chemistry, Vol. 64, Núm. 1, pp. 458-480

2017

  1. Enantiospecific Recognition at the A2B Adenosine Receptor by Alkyl 2-Cyanoimino-4-substituted-6-methyl-1,2,3,4-tetrahydropyrimidine-5-carboxylates

    Journal of Medicinal Chemistry, Vol. 60, Núm. 8, pp. 3372-3382

  2. Multicomponent Assembly of the Kinesin Spindle Protein Inhibitor CPUYJ039 and Analogues as Antimitotic Agents

    ACS Combinatorial Science, Vol. 19, Núm. 3, pp. 153-160

2014

  1. Structure-based design of new KSP-Eg5 inhibitors assisted by a targeted multicomponent reaction

    ChemBioChem, Vol. 15, Núm. 10, pp. 1471-1480

2013

  1. Discovery of 3,4-dihydropyrimidin-2(1 H)-ones as a novel class of potent and selective A2B adenosine receptor antagonists

    ACS Medicinal Chemistry Letters, Vol. 4, Núm. 11, pp. 1031-1036

  2. Selective and potent adenosine A3 receptor antagonists by methoxyaryl substitution on the N-(2,6-diarylpyrimidin-4-yl)acetamide scaffold

    European Journal of Medicinal Chemistry, Vol. 59, pp. 235-242

2011

  1. Pyrimidine derivatives as potent and selective A3 adenosine receptor antagonists

    Journal of Medicinal Chemistry, Vol. 54, Núm. 2, pp. 457-471

2009

  1. Divergent solution-phase synthesis of diarylpyrimidine libraries as selective A3 adenosine receptor antagonists

    Journal of Combinatorial Chemistry, Vol. 11, Núm. 4, pp. 519-522

2008

  1. 2-Substituted 4-, 5-, and 6-[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones and 2-substituted 4,5-bis[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones as potent platelet aggregation inhibitors: Design, synthesis, and SAR studies

    Bioorganic and Medicinal Chemistry Letters, Vol. 18, Núm. 2, pp. 793-797

  2. Click chemistry approach to assembly proline mimetic libraries containing 1,4-substituted 1,2,3-triazoles

    Journal of Combinatorial Chemistry, Vol. 10, Núm. 3, pp. 372-375

1989

  1. Piperazine derivatives of benzimidazole as potential anthelmintics. Part 1: Synthesis and activity of methyl-5-(4-substituted piperazin-1-yl) benzimidazole-2-carbamates

    Pharmazie, Vol. 44, Núm. 9, pp. 606-607

  2. Pyridazine Derivatives, VII. Synthesis and Hypotensive Activity of 3‐Hydrazinocycloalkyl[1,2‐c]pyridazines and their Derivatives

    Archiv der Pharmazie, Vol. 322, Núm. 6, pp. 331-336

1988

  1. Pyridazine Derivatives, VI. Synthesis and Hypotensive Activity of 3‐Hydrazinethieno(2,3‐h)Cinnoline and its Derivatives

    Archiv der Pharmazie, Vol. 321, Núm. 10, pp. 735-738

1987

  1. Síntesis de ácidos 2- Aroilcicloalcanocarboxílicos a partir de cicloalcanonas: ácido 2-benzoilciclohexanocarboxílico

    Anales de química. Serie C, Química orgánica y bioquímica, Vol. 83, Núm. 2, pp. 257-258

1985

  1. Derivados de la piridazina II. Síntesis y actividad antihipertensora de 3-arilamino-6-hidrazinopiridazinas

    Anales de química. Serie C, Química orgánica y bioquímica, Vol. 81, Núm. 2, pp. 110-112

  2. Derivados de la piridazina, IV. Síntesis y actividad antihipertensora de 3-hidrazino-5,6-dihidrobenzo (h) cinolinas

    Anales de química. Serie C, Química orgánica y bioquímica, Vol. 81, Núm. 3, pp. 280-283

  3. Pyridazine derivatives, I. Synthesis and antihypertensive activity of 6-phenyl-5-aminomethyl-3-hydrazino pyridazines

    European Journal of Medicinal Chemistry, Vol. 20, Núm. 5, pp. 475-479