Publications by the researcher in collaboration with JOSE ANGEL FONTENLA GIL (21)

2023

  1. 8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies

    European Journal of Medicinal Chemistry, Vol. 248

2020

  1. Discovery and optimization of 3-thiophenylcoumarins as novel agents against Parkinson's disease: Synthesis, in vitro and in vivo studies

    Bioorganic Chemistry, Vol. 101

2017

  1. Aporphine alkaloids and their antioxidant medical application: From antineoplastic agents to motor dysfunction diseases

    Current Organic Chemistry, Vol. 21, Núm. 4, pp. 342-347

  2. MAO inhibitory activity of bromo-2-phenylbenzofurans: Synthesis,: in vitro study, and docking calculations

    MedChemComm, Vol. 8, Núm. 9, pp. 1788-1796

2015

  1. Anxiolytic-like effects of 7H-benzo[e]perimidin-7-one derivatives through elevated plus-maze test in mice

    Current Topics in Medicinal Chemistry, Vol. 15, Núm. 17, pp. 1750-1754

2014

  1. Comparison of the antidepressive effects of trans-resveratrol and 5-methoxy-7H-dibenzo[de,h]quinolin-7-one.

    Current topics in medicinal chemistry, Vol. 14, Núm. 2, pp. 234-238

  2. Synthesis, pharmacological study and docking calculations of new benzo[f]coumarin derivatives as dual inhibitors of enzymatic systems involved in neurodegenerative diseases

    Future Medicinal Chemistry, Vol. 6, Núm. 4, pp. 371-383

2013

  1. Novel (coumarin-3-yl)carbamates as selective MAO-B inhibitors: Synthesis, in vitro and in vivo assays, theoretical evaluation of ADME properties and docking study

    European Journal of Medicinal Chemistry, Vol. 63, pp. 151-161

2003

  1. New arylpiperazine derivatives with high affinity for α1A, D2 and 5-HT2A receptors

    Bioorganic and Medicinal Chemistry Letters, Vol. 13, Núm. 2, pp. 175-178

2000

  1. Butyrophenone analogues in the carbazole series as potential atypical antipsychotics: Synthesis and determination of affinities at D2, 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors

    European Journal of Medicinal Chemistry, Vol. 35, Núm. 1, pp. 83-95

  2. Conformationally constrained butyrophenones with affinity for dopamine (D1, D2, D4) and serotonin (5-HT(2A), 5-HT(2B), 5-HT(2C)) receptors: Synthesis of aminomethylbenzo[b]furanones and their evaluation as antipsychotics

    Journal of Medicinal Chemistry, Vol. 43, Núm. 24, pp. 4678-4693

1999

  1. Conformationally constrained butyrophenones with mixed dopaminergic (D2) and serotoninergic (5-HT2(A), 5-HT2(C)) affinities: Synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo- and - thienocycloalkanones as putative atypical antipsychotics

    Journal of Medicinal Chemistry, Vol. 42, Núm. 15, pp. 2774-2797

1998

  1. Butyrophenone analogues in the carbazole series: Synthesis and determination of affinities at D2 and 5-HT(2A) receptors

    Bioorganic and Medicinal Chemistry Letters, Vol. 8, Núm. 24, pp. 3571-3576

1997

  1. New cyclic butyrophenone derivatives in the indole series as potential atypical antipsychotics. A simple and practical synthesis of 6-aminomethyl-tetrahydroindol-4-ones and their affinities for D2 and 5-HT(2A) receptors

    Bioorganic and Medicinal Chemistry Letters, Vol. 7, Núm. 7, pp. 913-918

1996

  1. Synthesis and affinities for dopamine (D2) and 5-hydroxytryptamine (5-HT2A) receptors of 1-(benzoylpropyl)-4-(1-oxocycloalkyl-2-ethyl)-piperazines as cyclic butyrophenone derivatives

    Chemical and Pharmaceutical Bulletin, Vol. 44, Núm. 3, pp. 534-541

1995

  1. Butyrophenone analogues: Synthesis of 2-methyl-3-ethyl-5-aminoethyl-4,5,6,7-tetrahydroindol-4-ones, and their affinities for d 1 , d 2 and 5-ht 2a receptors

    Bioorganic and Medicinal Chemistry Letters, Vol. 5, Núm. 6, pp. 579-584

1991

  1. Synthesis and Antidopaminergic Activity of Some 3-(Aminomethyl)tetralones as Analogues of Butyrophenone

    Journal of Medicinal Chemistry, Vol. 34, Núm. 7, pp. 2242-2247

1989

  1. Pyridazine Derivatives, VII. Synthesis and Hypotensive Activity of 3‐Hydrazinocycloalkyl[1,2‐c]pyridazines and their Derivatives

    Archiv der Pharmazie, Vol. 322, Núm. 6, pp. 331-336

1988

  1. Pyridazine Derivatives, VI. Synthesis and Hypotensive Activity of 3‐Hydrazinethieno(2,3‐h)Cinnoline and its Derivatives

    Archiv der Pharmazie, Vol. 321, Núm. 10, pp. 735-738

1985

  1. Derivados de la piridazina II. Síntesis y actividad antihipertensora de 3-arilamino-6-hidrazinopiridazinas

    Anales de química. Serie C, Química orgánica y bioquímica, Vol. 81, Núm. 2, pp. 110-112