I+D de fármacos
GI-1606
Francisco
Orallo Cambeiro
Publicaciones en las que colabora con Francisco Orallo Cambeiro (23)
2012
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Monoamino oxidase A: An interesting pharmacological target for the development of multi-target QSAR
Mini-Reviews in Medicinal Chemistry, Vol. 12, Núm. 10, pp. 947-958
2011
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Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors
Journal of Medicinal Chemistry, Vol. 54, Núm. 14, pp. 5165-5173
2010
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Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B
Bioorganic and Medicinal Chemistry Letters, Vol. 20, Núm. 9, pp. 2709-2712
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Synthesis and vasorelaxant and platelet antiaggregatory activities of a new series of 6-Halo-3-phenylcoumarins
Molecules, Vol. 15, Núm. 1, pp. 270-279
2009
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A new series of 3-phenylcoumarins as potent and selective MAO-B inhibitors
Bioorganic and Medicinal Chemistry Letters, Vol. 19, Núm. 12, pp. 3268-3270
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Alignment-free prediction of a drug-target complex network based on parameters of drug connectivity and protein sequence of receptors
Molecular Pharmaceutics, Vol. 6, Núm. 3, pp. 825-835
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Synthesis and evaluation of 6-methyl-3-phenylcoumarins as potent and selective MAO-B inhibitors
Bioorganic and Medicinal Chemistry Letters, Vol. 19, Núm. 17, pp. 5053-5055
2008
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Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors
Journal of Medicinal Chemistry, Vol. 51, Núm. 21, pp. 6740-6751
2007
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Quantitative structure vasodilatory activity relationship - Synthesis and "in silico" and "in vitro" evaluation of resveratrol-coumarin hybrids
QSAR and Combinatorial Science, Vol. 26, Núm. 3, pp. 317-332
2006
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Design, synthesis, and vasorelaxant and platelet antiaggregatory activities of coumarin-resveratrol hybrids
Bioorganic and Medicinal Chemistry Letters, Vol. 16, Núm. 2, pp. 257-261
2004
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Effects of cis-resveratrol on inflammatory murine macrophages: Antioxidant activity and down-regulation of inflammatory genes
Journal of Leukocyte Biology, Vol. 75, Núm. 6, pp. 1156-1165
2003
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In vivo and in vitro pharmacological studies of a new hypotensive compound (QF0301B) in rat: Comparison with prazosin, a known α1- adrenoceptor antagonist
Vascular Pharmacology, Vol. 40, Núm. 2, pp. 97-108
2002
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Synthesis and vasorelaxant activity of new coumarin and furocoumarin derivatives
Bioorganic and Medicinal Chemistry Letters, Vol. 12, Núm. 5, pp. 783-786
2000
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Study of the in vivo and in vitro cardiovascular effects of four new analogues of ketanserin: Implication of 5-HT(2A) and α1 adrenergic antagonism in their hypotensive effect
Biological and Pharmaceutical Bulletin, Vol. 23, Núm. 5, pp. 558-565
1998
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Preliminary study of the potential vasodilator effects on rat aorta of centaurein and centaureidin, two flavonoids from Centaurea corcubionensis
Planta Medica, Vol. 64, Núm. 2, pp. 116-119
1991
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Pyridazine Derivatives, VIII1): Synthesis and Antihypertensive Activity of 6‐(2‐Thienyl)‐5‐aminomethyl‐3‐hydrazino‐pyridazines
Archiv der Pharmazie, Vol. 324, Núm. 7, pp. 455-460
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Synthesis and Antidopaminergic Activity of Some 3-(Aminomethyl)tetralones as Analogues of Butyrophenone
Journal of Medicinal Chemistry, Vol. 34, Núm. 7, pp. 2242-2247
1989
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Pyridazine Derivatives, VII. Synthesis and Hypotensive Activity of 3‐Hydrazinocycloalkyl[1,2‐c]pyridazines and their Derivatives
Archiv der Pharmazie, Vol. 322, Núm. 6, pp. 331-336
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SINTESIS DE 2-AMINOMETILTETRALINAS COMO AGENTES α-BLOQUEANTES Y ANTIDOPAMINERGICOS
Anales de la Real Academia de Farmacia, Vol. 55, Núm. 4, pp. 461-469
1988
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Pyridazine Derivatives, VI. Synthesis and Hypotensive Activity of 3‐Hydrazinethieno(2,3‐h)Cinnoline and its Derivatives
Archiv der Pharmazie, Vol. 321, Núm. 10, pp. 735-738