Drug R&D
GI-1606
ERNESTO
CANO RUBIO
Researcher in the period 1989-2018
Publications by the researcher in collaboration with ERNESTO CANO RUBIO (9)
2017
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3-Oxopyridazin-5-yl-Chalcone Hybrids: Potent Antiplatelet Agents That Prevent Glycoprotein IIb/IIIa Activation
ChemistrySelect, Vol. 2, Núm. 17, pp. 4920-4933
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Synthesis and vasorelaxant and antiplatelet activities of a new series of (4-Benzylphthalazin-1-ylamino)alcohol derivatives
Medicinal Chemistry Research, Vol. 26, Núm. 8, pp. 1682-1688
2012
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Discovery and preliminary SAR of 5-arylidene-2,2-dimethyl-1,3-dioxane-4,6- diones as platelet aggregation inhibitors
Combinatorial Chemistry and High Throughput Screening, Vol. 15, Núm. 7, pp. 551-554
2008
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2-Substituted 4-, 5-, and 6-[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones and 2-substituted 4,5-bis[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones as potent platelet aggregation inhibitors: Design, synthesis, and SAR studies
Bioorganic and Medicinal Chemistry Letters, Vol. 18, Núm. 2, pp. 793-797
2007
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Design, synthesis, and structure-activity relationships of a novel series of 5-alkylidenepyridazin-3(2H)-ones with a non-cAMP-based antiplatelet activity
Journal of Medicinal Chemistry, Vol. 50, Núm. 26, pp. 6476-6484
2006
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Design, synthesis, and vasorelaxant and platelet antiaggregatory activities of coumarin-resveratrol hybrids
Bioorganic and Medicinal Chemistry Letters, Vol. 16, Núm. 2, pp. 257-261
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Pyridazines part 41: Synthesis, antiplatelet activity and SAR of 2,4,6-substituted 5-(3-oxo-3-phenylprop-1-en-1-yl)- or 5-(3-phenylprop-2-enoyl) pyridazin-3(2H)-ones
Bioorganic and Medicinal Chemistry Letters, Vol. 16, Núm. 4, pp. 1080-1083
2004
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Pyridazines. Part 36: Synthesis and antiplatelet activity of 5-substituted-6-phenyl-3(2H)-pyridazinones
Bioorganic and Medicinal Chemistry Letters, Vol. 14, Núm. 2, pp. 321-324
1999
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AM1 theoretical study, synthesis and biological evaluation of some benzofuran analogues of anti-inflammatory arylalkanoic acids
European Journal of Pharmaceutical Sciences, Vol. 7, Núm. 2, pp. 161-166