Engineering smart nano metal-organic frameworks for biomedical applications
- Cedrún Morales, Manuela
- Pablo Alfonso del Pino González de la Higuera Director
- Pablo Taboada Antelo Director
Universidade de defensa: Universidade de Santiago de Compostela
Fecha de defensa: 28 de xuño de 2024
- Jesús Martínez de la Fuente Presidente/a
- Patricia Díaz Rodríguez Secretario/a
- Sergio Mercado Argandona Vogal
Tipo: Tese
Resumo
This thesis aims to advance nanomedicine by developing nano metal-organic frameworks for enhanced drug delivery. Various systems were synthesized and tailored to investigate their encapsulation abilities and surface modi ications to provide them with targeting capabilities. Additionally, nanocomposites responsive to near-infrared (NIR) light were created, comprising a core of gold nanoparticles and a shell of nano metal-organic frameworks. These intelligent nanocarriers were designed to facilitate intracellular cargo delivery through innovative strategies.