Silicone Hydrogels Materials for Contact Lens Applications

  1. José M. González-Méijome 4
  2. Javier González-Pérez 3
  3. Paulo R.B. Fernandes 2
  4. Daniela P. Lopes-Ferreira 2
  5. Sergio Mollá 1
  6. Vicente Compañ 1
  1. 1 Department of Applied Th ermodynamics, Technical College of Mechanical Engineering, PolytechnicUniversity of Valencia, Valencia, Spain
  2. 2 Clinical and Experimental Optometry Research Laboratory (CEORLab) – Center of Physics (Optometry),School of Sciences, University of Minho, Braga, Portugal
  3. 3 Ocular Surface and Contact Lens Research Group, Faculty of Optics and Optometry, University of Santiago de Compostela, Coruña, Spain
  4. 4 1Clinical and Experimental Optometry Research Laboratory (CEORLab) – Center of Physics (Optometry),School of Sciences, University of Minho, Braga, Portugal
Libro:
Concise Encyclopedia of High Performance Silicones

Editorial: Wiley

ISBN: 978-1-118-46965-1

Ano de publicación: 2012

Páxinas: 293-284

Tipo: Capítulo de libro

Resumo

Silicone hydrogel (Si-Hy) materials combine the benefi ts of silicone or siloxane derivates in terms of oxygen permeability and mechanical properties with those of hydrogels in terms of wettability and hidrophilicity. Such properties are critical when it comes to the application at the ocular surface in the form of contact lenses (CL) to correct visual dysfunctions, as bandage mechanism or as drug deliverydevices. Nowadays, CL are used by over 100 million people worldwide.Silicone hydrogel materials applied in the production of CL are a good example of how challenging the ocular surface environmentis when it comes to the engineering of devices that will be well tolerated in this part of the human body. We now face the challenge ofunderstanding the interaction between these materials and the disinfecting and cleaning systems, how these can impact the integrityof the ocular surface and the risks of infl ammatory adverse events, and how wearing comfort can be improved.