Marcadores moleculares en el cáncer de mama. Implicaciones terapéuticas
- Cebey López, V. 1
- Álvarez Fernández, J. 1
- Palacios Ozores, P. 1
- Cortegoso Mosquera, A. 1
- López López, R. 1
- 1 Servicio de Oncología Médica y Grupo de Oncología Médica Traslacional, Hospital Clínico Universitario e Instituto de Investigación Sanitaria-CIBERONC, Santiago de Compostela, La Coruña, España
ISSN: 0304-5412
Año de publicación: 2021
Título del ejemplar: Enfermedades oncológicas (IV)Melanoma, cáncer de mama y tumores ginecológicos
Serie: 13
Número: 27
Páginas: 1543-1545
Tipo: Artículo
Otras publicaciones en: Medicine: Programa de Formación Médica Continuada Acreditado
Resumen
Breast cancer is one of the tumor types in which the use of biomarkers has been earlier incorporated into clinical practice and in the greatest number. Biomarkers are classified into two groups: prognostic markers and predictive response markers, but some of them belong to both groups. Biomarkers, including immunohistochemistry markers (like estrogen, progesterone receptors, HER2 and Ki67) and current ones based mainly on gene (BRCA, PI3K) and immune system (PD-L1, TILS) expression, are essential in disease classification and treatment choice. Nowadays, molecular and liquid-biopsy platforms, are being validated.
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