Utilización de las sales aniónicas en la prevención de la paresia puerperal hipocalcémica

  1. L. Espino 1
  2. M. L. Suárez 1
  3. G. Santamarina 1
  4. A. Goicoa 1
  5. L. E. Fidalgo 1
  1. 1 Universidad de Santiago de Compostela Facultad de Veterinaria de Lugo Departamento de Ciencias Clínicas Veterinarias
Revista:
Archivos de Medicina Veterinaria

ISSN: 0301-732X,  0717-6201

Ano de publicación: 2005

Volume: 37

Número: 1

Páxinas: 7-13

Tipo: Artigo

DOI: 10.4067/S0301-732X2005000100002 DIALNET GOOGLE SCHOLAR lock_openAcceso aberto editor

Outras publicacións en: Archivos de Medicina Veterinaria

Obxectivos de Desenvolvemento Sustentable

Resumo

La fiebre de leche es una de las enfermedades metabólicas más frecuentes en el ganado bovino de leche. De los diferentes métodos empleados para la prevención de esta enfermedad, el manejo dietético es el que más ha evolucionado. Muchos investigadores han comprobado que la adición de sales aniónicas a la ración disminuye la incidencia de la fiebre de leche. Las sales aniónicas se incluyen en la dieta de las vacas secas durante 2-3 semanas antes del parto para inducir un estado de acidosis metabólica leve. El mecanismo de acción preciso de los aniones de la dieta no está bien establecido. En estudios previos se ha sugerido que la acidosis metabólica inducida por las sales aniónicas incrementa la respuesta de los tejidos a la hormona paratiroidea, mejora la absorción intestinal de calcio y aumenta la reabsorción ósea de calcio. En este trabajo, revisamos el concepto de diferencial catión-anión de la dieta, con especial énfasis en los efectos fisiológicos que éste puede ejercer en el estado ácido-base, reabsorción ósea, producción renal de 1,25 (OH)2 D3, reabsorción renal de calcio y absorción intestinal de calcio en vacas.

Referencias bibliográficas

  • Abu-Damir, H,Phillippo, M,Thorp, BH,Milne, JS,Dick, L,Nevison, IM. (1994). Effects of dietary acidity on calcium balance and mobilization, bone morphology and 1,25 dihydroxivitamin D in prepartal dairy cows. Res Vet Sci. 56.
  • Akeno, N,Matsunuma, A,Maeda, T,Kawane, T,Horiuchi, N. (2000). Regulation of vitamin-D-1-alpha-hydroxylase and 24- hydroxylase expression by dexamethasone in mouse kidney. J Endocrinol. 164.
  • Bailey, JE,Pablo, LS. (1998). Practical approach to acid-base disorders. Vet Clin North Am Small Anim Pract. 28.
  • Beck, N,Webster, SK. (1976). Effects of acute metabolic acidosis on parathyroid hormone action and calcium mobilization. Am J Physiol. 230.
  • Block, E.. (1984). Manipulating dietary anions and cations for prepartum dairy cows to reduce incidence of milk fever. J Dairy Sci. 67.
  • Bushinsky, DA.. (1989). Net calcium efflux from live bone during chronic metabolic, but not respiratory, acidosis. Am J Physiol Renal Fluid Electrolyte Physiol. 256.
  • De Blas, C,Resch, C,Amor, J,García, P. (1999). Utilización de sales aniónicas en dietas para vacas secas. Prod Anim. 141.
  • Delaquis, AM,Block, E. (1995). Dietary cation-anion difference, acid-base status, mineral metabolism, renal function, and milk production of lactating cows. J Dairy Sci. 78.
  • Dishington, IW.. (1975). Prevention of milk fever (hypocalcemic paresis puerperalis) by dietary salt supplements. Acta Vet Scand. 16.
  • Ender, F,Dishington, IW,Helgebostad, A. (1971). Calcium balance studies in dairy cows under experimental induction and prevention of hypocalcaemic paresis puerperalis: The solution of the aetiology and the prevention of milk fever by dietary means. Z Tierphysiol Tierernaehr Futtermittelkd. 28.
  • Espino, L.. (2003). Efectos de la diferencia de cationes y aniones de la dieta en la homeostasis ácido-base y mineral y en la morfología ósea en ovejas.
  • Espino, L.,Guerrero, F,Suárez, ML,Santamarina, G,Goicoa, A,Fidalgo, LE. (2003). Long-term effects of dietary anion-cation balance on acid-base status and bone morphology in reproducing ewes. J Vet Med A. 50.
  • Gant, RG,Sánchez, W,Kincaid, RL. (1998). Effect of anionic salts on selenium metabolism in nonlactanting, pregnant dairy cows. J Dairy Sci. 81.
  • Goff, JP.. (2000). Pathophysiology of calcium and phosphorus disorders. Vet Clin North Am Food Pract. 16.
  • Goff, JP.,Horst, RL. (1997). Effects of the addition of potassium or sodium, but not calcium, to prepartum rations on milk fever in dairy cows. J Dairy Sci. 80.
  • Horst, RL,Goff, JP.. (1998). Use of hydrochloric acid as a source of anions for prevention of milk fever. J Dairy Sci. 81.
  • Goff, JP.,Horst, RL. (2003). Role of acid-base physiology on the pathogenesis of parturient hypocalcaemia (Milk fever)-the DCAD theory in principal and practice. Act Vet Scand. 97.
  • Horst, RL,Goff, JP.,Mueller, FJ,Miller, JK,Kiess, GA,Dowlen, HH. (1991). Addition of chloride to a prepartal diet high in cations increases 1,25-dihydroxyvitamin D response to hypocalcemia preventing milk fever. J Dairy Sci. 74.
  • Horst, RL,Reindhart, TA,Horst, RL. (1995). Milk fever and dietary cation-anion balance effects on concentration of vitamin D receptor in tissue of periparturient dairy cows. J Dairy Sci. 78.
  • Horst, RL,Goff, JP,Reinhardt, AT,Buxton, DR. (1997). Strategies for preventing milk fever in dairy cattle. J Dairy Sci. 80.
  • Howard, JL,Smith, RA. (1999). Current veterinary therapy 4: food animal practice. 4. W.B Saunders. Philadelphia.
  • Joyce, PW,Sánchez, WK,Goff, JP. (1997). Effect of anionic salts in prepartum diets based on alfalfa. J Dairy Sci. 80.
  • Lomba, F,Chauvaux, G,Teller, E,Lengels, L,Bienfet, V. (1978). Calcium digestibility in cows as influenced by the excess of alkaline ions over stable acid ions in their diets. Br J Nutr. 39.
  • Martin, KJ,Freitag, JJ,Bellorin-Font, E,Conrades, MB,Khlar, S,Slatopolsky, E.. (1980). The effect of acute acidosis on the uptake of parathyroid hormone and the production of adenosine 3’,5’-monophosphate by isolated perfused bone. Endocrinology. 106.
  • Maurer, M,Riensen, W,Muser, J,Hulter, HN,Krapf, R. (2003). Neutralization of Western diet inhibits bone resorption independently of K intake and reduces cortisol secretion in humans. Am J Physiol Renal Physiol. 284.
  • May, RC,Kelly, RA,Mitch, WE. (1986). Metabolic acidosis stimulates protein degradation in rat muscle by a glucocorticoid- dependent mechanism. J Clin Invest. 77.
  • Mellau, LSB,Jorgensen, RJ,Kambarage, DM. (2002). The influence of short-term anion salt exposure on urine pH and on resistance to experimentally induced hypocalcaemia in cows. J Vet Med A. 49.
  • Midorikawa, K,Sayama, DM,Shirakata, Y,Hanakawa, Y,Sun, L,Hashimoto, K. (1999). Expression of vitamin D receptor in cultured human keratinocytes and fibroblasts is not altered by corticoesteroids. J Dermatol Sci. 21.
  • Morrissey, JJ,Cohn, DN. (1978). The effects of calcium and magnesium on the secretion of parathormone and parathyroid secretory protein by isolated porcine parathyroid cells. Endocrinology. 103.
  • Oetzel, GR,Barmore, JA. (1993). Intake of a concentrate mixture containing various anionic salts to pregnant, non lactating dairy cows. J Dairy Sci. 76.
  • Oetzel, GR,Olson, JD,Curtis, CR,Fettman, MJ. (1988). Ammonium chloride and ammonium sulfate for prevention of parturient paresis in dairy cows. J Dairy Sci. 71.
  • Oetzel, GR,Fettman, MJ,Hamar, DW,Olson, JD. (1991). Screening of anionic salts for palatability, effects on acid-base status and urinary calcium excretion in dairy cows. J Dairy Sci. 74.
  • Pehrson, B,Svensson, C,Gruvaeus, I,Virkki. (1999). The influence of acidic diets on the acid-base balance of dry cows and the effect of fertilization on the mineral content of grass. J Dairy Sci. 82.
  • Phillippo, M,Reid, GW,Nevison, IM. (1994). Parturient hypocalcaemia in dairy cows: effects of dietary acidity on plasma minerals and calciotrophic hormones. Res Vet Sci. 56.
  • Roche, JR,Dalley, D,Moate, P,Grainger, C,Rath, M,O’Mara, F. (2003). Dietary cation-anion difference and the health and production of pasture-fed dairy cows 2. Nonlactating periparturient cows. J Dairy Sci. 86.
  • Sachs, M,Bar, A,Cohen, R,Mazur, Y,Mayer, E,Hurwitz, S. (1977). Use of 1-a-hydroxycholecalciferol in the prevention of bovine parturient paresis. Am J Vet Res. 38.
  • Schonewille, JT,Van’t Klooster, AT,Wourtese, H,Beynen, AC. (1999). Hypocalcemia induced by intravenous administration of disodium ethylenedaminotetracetate and its effects on excretion of calcium in urine of cows fed a high chloride diet. J Dairy Sci. 82.
  • Shaver, R,Oetzel, G. (1990). New feed ingredients may help prevent milk fever. Hoard’s Dairyman. 135.
  • Stewart, PA.. (1983). Modern quantitative acid-base chemistry. Can J Physiol Phayrmacol. 61.
  • Takagi, H,Block, E. (1991). Effects of manipulating dietary cationanion balance on macromineral balance in sheep. J Dairy Sci. 74.
  • Tucker, WB,Hogue, JF,Adams, GD,Aslam, M,Shin, LS,Morgan, G. (1992). Influence of dietary cation-anion balance during the dry period on the occurrence of parturient paresis in cows fed excess calcium. J Anim Sci. 70.
  • Vagnoni, DB,Oetzel, GR. (1998). Effects of dietary cation-anion difference on the acid-base status of dry cows. J Dairy Sci. 81.
  • Van Dijk, CJ,Lourens, DC. (2001). Effects of anionic salts in a prepartum dairy ration on calcium metabolism. J S Afr Vet Assoc. 72.
  • Van Mosel, M,Van’t Klooster, AT,Van Mosel, F,Van Der Kuilen, J. (1993). Effects of reducing dietary (Na + K) - (Cl + SO4) on the rate of calcium mobilization by dairy cows at parturition. Res Vet Sci. 54.
  • Wang, C,Beede, DK. (1992). Effects of diet ammonium chloride and sulfate on acid-base status and calcium metabolism of dry Jersey cows. J Dairy Sci. 75.
  • West, JW,Haydon, KD,Mullinix, BG,Dandifer, TG. (1992). Cationanion balance and cation source effects on acid-base status of heat-stressed cows. J Dairy Sci. 75.
  • Whiting, SJ,Draper, HH. (1981). Effect of chronic acid load as sulfate or sulfur amino acids on bone metabolism in adult rats. J Nutr. 111.
Fonte de datos: Dialnet