Uso de naltrexona en la deshabituación de pacientes con dependencia de alcohol en el estado español

  1. Mercedes Izquierdo Serrano 1
  2. A. Rodríguez Martos 2
  3. J. Llopis 3
  4. B. Cañuelo 4
  5. G. Guigou 5
  6. J. Izquierdo 6
  7. A. Lorenzo 7
  8. M. Mateo 8
  9. G. Rubio 9
  10. J. Varo 10
  1. 1 Unidad de Alcoholismo.Complejo Sanitario Provincial. Plasencia.
  2. 2 Plan de Acción sobre Drogas de Barcelona
  3. 3 Unidad de Conductas Adictivas. Centro de Salud San Agustin. Castellón
  4. 4 Centro de Toxicomanias Cruz Roja. Cordoba
  5. 5 CAD Sta. Cruz de Tenerife
  6. 6 Centro Comarcal Palma Periferia. Palma de Mallorca.
  7. 7 Servicio de Psiquiatría. Hospital General de Galicia. Santiago de Compostela
  8. 8 Hospital Divino Vallés. Burgos
  9. 9 Hospital Psiquiátrico Sagrado Corazón de Jesús. Madrid
  10. 10 Centro de Salud Mental de Ermitagaña. Pamplona
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Revista:
Adicciones: Revista de socidrogalcohol

ISSN: 0214-4840

Ano de publicación: 2002

Volume: 14

Número: 3

Páxinas: 327-335

Tipo: Artigo

DOI: 10.20882/ADICCIONES.488 DIALNET GOOGLE SCHOLAR lock_openAcceso aberto editor

Outras publicacións en: Adicciones: Revista de socidrogalcohol

Resumo

Objectives: to describe the profile of alcoholic patients who most benefit from naltrexone treatment, and to show its utility in decreasing craving, relapses and consumption episodes. Methods: multicentre and observational study with a naturalistic design. 321alcohol- dependent patients (DSM-IV) treated with naltrexone were studied and followed up over 9 months. Results: the responder/ non-responder patient profile showed only differences concerning the educational level (p=0.039) and work situation (p=0.041). The outcome analysis showed the following percentages: 45.4% total abstinence or absence of alcohol consumption; 7.2% some consumption and 27.3% relapses. Discussion: It has not been possible to describe the profile of the alcoholic patient who would benefit the most from naltrexone. Limitations of the study derive from the heterogeneous sample and from the lack of a control group with random allocation of cases. More studies are needed in order to identify the predictive factors for a therapeutic response. However, this study has not only confirmed the usefulness of naltrexone in decreasing the quantity and frequency of alcohol consumption, but its long term follow-up (9 months) allowed verification of the additional benefit of a protracted treatment. After 9 months, there is also an increase in the number of patients who are able to control their consumption without fulfilling relapse criteria.

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Fonte de datos: Dialnet