XERARDO XUSTO
GARCIA MERA
Catedrático de universidad
Jhonny Alberto
Azuaje Guerrero
Publicaciones en las que colabora con Jhonny Alberto Azuaje Guerrero (18)
2024
2023
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Exploring the Effect of Halogenation in a Series of Potent and Selective A2BAdenosine Receptor Antagonists
Journal of Medicinal Chemistry, Vol. 66, Núm. 1, pp. 890-912
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Pharmacological insights emerging from the characterization of a large collection of synthetic cannabinoid receptor agonists designer drugs
Biomedicine and Pharmacotherapy, Vol. 164
2022
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A 2B adenosine receptor antagonists rescue lymphocyte activity in adenosine-producing patient-derived cancer models
Journal for ImmunoTherapy of Cancer, Vol. 10, Núm. 5
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Exploring Non-orthosteric Interactions with a Series of Potent and Selective A3Antagonists
ACS Medicinal Chemistry Letters, Vol. 13, Núm. 2, pp. 243-249
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Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A1Antagonists
Journal of Medicinal Chemistry, Vol. 65, Núm. 3, pp. 2091-2106
2021
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3,4-Dihydropyrimidin-2(1H)-ones as Antagonists of the Human A2B Adenosine Receptor: Optimization, Structure-Activity Relationship Studies, and Enantiospecific Recognition
Journal of medicinal chemistry, Vol. 64, Núm. 1, pp. 458-480
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Catalytic performance of a metal-free graphene oxide-Al2O3 composite assembled by 3D printing
Journal of the European Ceramic Society, Vol. 41, Núm. 2, pp. 1399-1406
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Potent and Subtype-Selective Dopamine D2Receptor Biased Partial Agonists Discovered via an Ugi-Based Approach
Journal of Medicinal Chemistry, Vol. 64, Núm. 12, pp. 8710-8726
2020
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Nitrogen-Walk Approach to Explore Bioisosteric Replacements in a Series of Potent A2B Adenosine Receptor Antagonists
Journal of medicinal chemistry, Vol. 63, Núm. 14, pp. 7721-7739
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X-Ray Crystallography and Free Energy Calculations Reveal the Binding Mechanism of A2A Adenosine Receptor Antagonists
Angewandte Chemie - International Edition, Vol. 59, Núm. 38, pp. 16536-16543
2019
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Trifluorinated Pyrimidine-Based A2B Antagonists: Optimization and Evidence of Stereospecific Recognition
Journal of Medicinal Chemistry, Vol. 62, Núm. 20, pp. 9315-9330
2017
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Development of Fluorescent Probes that Target Serotonin 5-HT2B Receptors
Scientific Reports, Vol. 7, Núm. 1
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Enantiospecific Recognition at the A2B Adenosine Receptor by Alkyl 2-Cyanoimino-4-substituted-6-methyl-1,2,3,4-tetrahydropyrimidine-5-carboxylates
Journal of Medicinal Chemistry, Vol. 60, Núm. 8, pp. 3372-3382
2016
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Discovery of Potent and Highly Selective A2B Adenosine Receptor Antagonist Chemotypes
Journal of Medicinal Chemistry, Vol. 59, Núm. 5, pp. 1967-1983
2014
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Structure-based design of new KSP-Eg5 inhibitors assisted by a targeted multicomponent reaction
ChemBioChem, Vol. 15, Núm. 10, pp. 1471-1480
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Ugi-based approaches to quinoxaline libraries
ACS Combinatorial Science, Vol. 16, Núm. 8, pp. 403-411
2013
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Discovery of 3,4-dihydropyrimidin-2(1 H)-ones as a novel class of potent and selective A2B adenosine receptor antagonists
ACS Medicinal Chemistry Letters, Vol. 4, Núm. 11, pp. 1031-1036