Publicacións (56) Publicacións de MARIA OLGA CAAMAÑO SANTOS

filter_list Organic Chemistry

2020

  1. Nitrogen-Walk Approach to Explore Bioisosteric Replacements in a Series of Potent A2B Adenosine Receptor Antagonists

    Journal of medicinal chemistry, Vol. 63, Núm. 14, pp. 7721-7739

2019

  1. Trifluorinated Pyrimidine-Based A2B Antagonists: Optimization and Evidence of Stereospecific Recognition

    Journal of Medicinal Chemistry, Vol. 62, Núm. 20, pp. 9315-9330

2018

  1. One-pot preparation and characterisation of five-membered cyclic alcohols

    Letters in Organic Chemistry, Vol. 15, Núm. 6, pp. 546-550

2017

  1. Advances towards the synthesis and characterization of five-membered cyclic alcohols and ketones

    Chemical Data Collections

  2. An efficient and recyclable 3D printed α-Al2O3 catalyst for the multicomponent assembly of bioactive heterocycles

    Applied Catalysis A: General, Vol. 530, pp. 203-210

  3. Effect of Nitrogen Atom Substitution in A3 Adenosine Receptor Binding: N-(4,6-Diarylpyridin-2-yl)acetamides as Potent and Selective Antagonists

    Journal of Medicinal Chemistry, Vol. 60, Núm. 17, pp. 7502-7511

2016

  1. Novel l-prolyl-l-leucylglycinamide (PLG) tripeptidomimetics based on a 2-azanorbornane scaffold as positive allosteric modulators of the D2R

    Organic and Biomolecular Chemistry, Vol. 14, Núm. 47, pp. 11065-11069

2015

  1. A click chemistry approach to the synthesis of 3′-deoxy-2′-substituted carbanucleoside precursors

    Tetrahedron, Vol. 71, Núm. 2, pp. 324-331

2013

  1. Copper-catalyzed huisgen 1,3-dipolar cycloaddition under oxidative conditions: Polymer-assisted assembly of 4-acyl-1-substituted-1,2,3-triazoles

    Journal of Organic Chemistry, Vol. 78, Núm. 13, pp. 6540-6549

2012

  1. A route to selective functionalization of polyhydroxypyrrolidines

    Tetrahedron Letters, Vol. 53, Núm. 9, pp. 1029-1032

2011

  1. Pyrimidine derivatives as potent and selective A3 adenosine receptor antagonists

    Journal of Medicinal Chemistry, Vol. 54, Núm. 2, pp. 457-471

  2. Silica-supported aluminum chloride-assisted solution phase synthesis of pyridazinone-based antiplatelet agents

    ACS Combinatorial Science, Vol. 13, Núm. 1, pp. 7-12

2010

  1. A 'click chemistry' approach to the straightforward synthesis of new 4-aryl-1,2,3-triazolocarbanucleosides

    Arkivoc, Vol. 2010, Núm. 3, pp. 152-168

  2. Design, synthesis, and evaluation of antineoplastic activity of novel carbocyclic nucleosides

    Molecular Informatics, Vol. 29, Núm. 3, pp. 213-231

  3. Polymer-supported 1,5,7-triazabicyclo [4.4.0] dec-5-ene as polyvalent ligands in the copper-catalyzed Huisgen 1,3-dipolar cycloaddition

    Advanced Synthesis and Catalysis, Vol. 352, Núm. 7, pp. 1179-1192

  4. Synthesis and pharmacological evaluation of novel 1,3,8- and 1,3,7,8-substituted xanthines as adenosine receptor antagonists

    Bioorganic and Medicinal Chemistry, Vol. 18, Núm. 5, pp. 2001-2009

  5. Synthesis of methyl (±)-3,5-bis(substitutedmethyl)pyrrolidine-2- carboxylates: A convenient approach to proline-mimetics

    Tetrahedron, Vol. 66, Núm. 34, pp. 6797-6805

2009

  1. 1,3-Dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships

    Bioorganic and Medicinal Chemistry, Vol. 17, Núm. 10, pp. 3618-3629

  2. Synthesis and biological evaluation of 6-substituted purinylcarbanucleosides with a cyclopenta[b]thiophene pseudosugar

    Synthesis, pp. 2766-2772

  3. Synthesis of novel 1-alkyl-8-substituted-3-(3-methoxypropyl) xanthines as putative A2B receptor antagonists

    Bioorganic and Medicinal Chemistry, Vol. 17, Núm. 9, pp. 3426-3432