Catálise Organometálica e Materiais Moleculares Orgánicos
COMMO (GI-1595)
MARIA
MANEIRO REY
Investigadora no período 2018-2024
Publicacións nas que colabora con MARIA MANEIRO REY (11)
2023
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Quinate-based ligands for irreversible inactivation of the bacterial virulence factor DHQ1 enzyme—A molecular insight †
Frontiers in Molecular Biosciences, Vol. 10
2021
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6-Halopyridylmethylidene Penicillin-Based Sulfones Efficiently Inactivate the Natural Resistance of Pseudomonas aeruginosa to β-Lactam Antibiotics
Journal of Medicinal Chemistry, Vol. 64, Núm. 9, pp. 6310-6328
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Activity of imipenem, meropenem, cefepime, and sulbactam in combination with the β-lactamase inhibitor ln-1-255 against acinetobacter spp.
Antibiotics, Vol. 10, Núm. 2, pp. 1-15
2020
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6-Arylmethylidene Penicillin-Based Sulfone Inhibitors for Repurposing Antibiotic Efficiency in Priority Pathogens
Journal of Medicinal Chemistry, Vol. 63, Núm. 7, pp. 3737-3755
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Self-Immolation of a Bacterial Dehydratase Enzyme by its Epoxide Product
Chemistry - A European Journal, Vol. 26, Núm. 36, pp. 8035-8044
2019
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Hydroxylammonium derivatives for selective active-site lysine modification in the anti-virulence bacterial target DHQ1 enzyme
Organic Chemistry Frontiers, Vol. 6, Núm. 17, pp. 3127-3135
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Therapeutic Efficacy of LN-1-255 in Combination with Imipenem in Severe Infection Caused by Carbapenem-Resistant Acinetobacter baumannii
Antimicrobial Agents and Chemotherapy, Vol. 63, Núm. 10
2017
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Activity of the ß-Lactamase inhibitor LN-1-255 against carbapenem-hydrolyzing class D ß-Lactamases from acinetobacter baumannii
Antimicrobial Agents and Chemotherapy, Vol. 61, Núm. 11
2016
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Targeting the Motion of Shikimate Kinase: Development of Competitive Inhibitors that Stabilize an Inactive Open Conformation of the Enzyme
Journal of Medicinal Chemistry, Vol. 59, Núm. 11, pp. 5471-5487
2015
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Irreversible covalent modification of type i dehydroquinase with a stable Schiff base
Organic and Biomolecular Chemistry, Vol. 13, Núm. 3, pp. 706-716
2014
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Insights into substrate binding and catalysis in bacterial type i dehydroquinase
Biochemical Journal, Vol. 462, Núm. 3, pp. 415-424